MEF2C [p Ser222] Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-60774

Novus Biologicals, part of Bio-Techne
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Key Product Details

Validated by

Biological Validation

Species Reactivity

Validated:

Human

Predicted:

Bovine (100%), Chicken (100%), Guinea Pig (100%), Mouse (100%), Primate (100%), Rat (100%), Sheep (100%). Backed by our 100% Guarantee.

Applications

Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all MEF2C Antibodies »

Product Summary for MEF2C [p Ser222] Antibody

Immunogen

Synthetic phospho-peptide corresponding to amino acid residues surrounding Ser222 conjugated to KLH. Accession # Q06413

Modification

p Ser222

Specificity

Specific for endogenous levels of the ~51 kDa MEF2C protein phosphorylated at Ser222. Immunolabeling is completely eliminated by treatment with lambda-phosphatase.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

51 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for MEF2C [p Ser222] Antibody

Western Blot: MEF2C [p Ser222] Antibody [NBP2-60774]

Western Blot: MEF2C [p Ser222] Antibody [NBP2-60774]

Western Blot: MEF2C [p Ser222] Antibody [NBP2-60774] - Western blot of OCIAML2 lysate showing specificimmunolabeling of the ~51 kDa MEF2C phosphorylated atSer222 in the first lane (-). Phosphospecificity is shown in thesecond lane (+) where the immunolabeling is completelyeliminated by blot treatment with lambda phosphatase (Lambda-Ptase,1200 units for 30 minutes).

Applications for MEF2C [p Ser222] Antibody

Application
Recommended Usage

Western Blot

1:100-1:2000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Antigen Affinity-purified

Formulation

10 mM HEPES (pH 7.5), 0.15 M NaCl, 0.1 mg/mL BSA, 50% Glycerol

Preservative

No Preservative

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: MEF2C

Transcription activator which binds specifically to the MEF2 element present in the regulatory regions of many muscle-specific genes. Controls cardiac morphogenesis and myogenesis, and is also involved in vascular development. May also be involved in neurogenesis and in the development of cortical architecture . Isoform 3 and isoform 4, which lack the repressor domain, are more active than isoform 1 and isoform 2

Long Name

Myocyte-specific Enhancer Factor 2C

Alternate Names

DEL5q14.3

Gene Symbol

MEF2C

Additional MEF2C Products

Product Documents for MEF2C [p Ser222] Antibody

Product Datasheets

Certificate of Analysis

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Product Specific Notices for MEF2C [p Ser222] Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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