MEK1 Antibody (BLR096G)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-14688

Recombinant Monoclonal
Novus Biologicals, part of Bio-Techne
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NBP3-14688
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Key Product Details

Species Reactivity

Validated:

Human

Applications

Flow Cytometry, Immunoprecipitation, Western Blot

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit Clone # BLR096G

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all MEK1 Antibodies »

Product Summary for MEK1 Antibody (BLR096G)

Immunogen

between 343 and 393 (C-term)

Clonality

Monoclonal

Host

Rabbit

Scientific Data Images for MEK1 Antibody (BLR096G)

Immunoprecipitation: MEK1 Antibody (BLR096G) [NBP3-14688]

Immunoprecipitation: MEK1 Antibody (BLR096G) [NBP3-14688]

Immunoprecipitation: MEK1 Antibody [NBP3-14688] - : Whole cell lysate (1.0 mgper IP reaction; 20% of IP loaded) from HeLa cells preparedusing NETN lysis buffer. Antibodies: Rabbit anti-MEK1recombinant monoclonal antibody used for IP at 20 ul/mg lysate. MEK1 was alsoimmunoprecipitated by rabbit anti-MEK1 recombinantmonoclonal antibody. For blottingimmunoprecipitated MEK1, was used at 1:1000.Chemiluminescence with an exposure time of 30 seconds.

Applications for MEK1 Antibody (BLR096G)

Application
Recommended Usage

Flow Cytometry

Optimal dilutions of this antibody should be experimentally determined.

Immunoprecipitation

Optimal dilutions of this antibody should be experimentally determined.

Western Blot

Optimal dilutions of this antibody should be experimentally determined.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

>95%

Formulation

Borate Buffered Saline (BBS) pH 8.2 with 0.1% BSA and

Preservative

0.09% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 2 - 8 C / 1 year from date of receipt

Background: MEK1

MEK 1 (MAP Kinase Kinase, also known as MKK) is an integral component of the MAP kinase cascade that regulates cell growth and differentiation (Ahn, 1993; Chong et al., 2003). This pathway also plays a key role in synaptic plasticity in brain (Adams and Sweatt, 2002). Activated MEK 1 acts as a dual specificity kinase phosphorylating both a threonine and a tyrosine residue on MAP kinase (Kyriakis et al., 1991; Seger et al., 1991; Crews et al., 1992) Conversely there also appears to be a feedback phosphorylation of MEK 1 by MAP kinase. The sites on MEK 1 that are phosphorylated by MAP kinase are Thr292 and Thr386 (Mansour et al., 1994).

Long Name

Mitogen-activated Protein Kinase Kinase 1

Alternate Names

MAP2K1, MKK1

Gene Symbol

MAP2K1

Additional MEK1 Products

Product Documents for MEK1 Antibody (BLR096G)

Product Datasheets

Certificate of Analysis

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Product Specific Notices for MEK1 Antibody (BLR096G)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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