Melatonin R1A/MT1/MTNR1A Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-28912

Novus Biologicals, part of Bio-Techne
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Key Product Details

Species Reactivity

Validated:

Rat

Predicted:

Bovine (100%), Canine (100%), Human (100%), Mouse (100%). Backed by our 100% Guarantee.

Applications

Validated:

Peptide ELISA, Western Blot

Cited:

Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Goat IgG

Concentration

0.5 mg/ml

View all Melatonin R1A/MT1/MTNR1A Antibodies »

Product Specifications

Immunogen

Peptide with sequence C-SLKYDKLYSSKNS corresponding to internal region according to NP_005949.1.

Clonality

Polyclonal

Host

Goat

Isotype

IgG

Scientific Data Images for Melatonin R1A/MT1/MTNR1A Antibody

Western Blot: Melatonin R1A/MT1/MTNR1A Antibody [NBP1-28912]

Western Blot: Melatonin R1A/MT1/MTNR1A Antibody [NBP1-28912]

Western Blot: Melatonin R1A/MT1/MTNR1A Antibody [NBP1-28912] - Staining of Rat Retina lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour.Detected by chemiluminescence.

Applications for Melatonin R1A/MT1/MTNR1A Antibody

Application
Recommended Usage

Peptide ELISA

Detection limit 1:6000

Western Blot

0.3 - 1 ug/ml
Application Notes
WB: Approx. 45 kDa band observed in KELLY lysate (calculated MW of 39.4 kDa band according to NP_005949.1).

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

Tris saline (20 mM Tris pH 7.3, 150 mM NaCl), 0.5% BSA

Preservative

0.02% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: Melatonin R1A/MT1/MTNR1A

This gene encodes one of two high affinity forms of a receptor for melatonin, the primary hormone secreted by the pineal gland. This receptor is a G-protein coupled, 7-transmembrane receptor that is responsible for melatonin effects on mammalian circadian rhythm and reproductive alterations affected by day length. The receptor is an integral membrane protein that is readily detectable and localized to two specific regions of the brain. The hypothalamic suprachiasmatic nucleus appears to be involved in circadian rhythm while the hypophysial pars tuberalis may be responsible for the reproductive effects of melatonin. [provided by RefSeq]

Long Name

Melatonin Receptor 1A

Alternate Names

Mel-1A-R, MelatoninR1A, MT1, MTNR1A

Entrez Gene IDs

4543 (Human)

Gene Symbol

MTNR1A

UniProt

P48039 (Human)

Additional Melatonin R1A/MT1/MTNR1A Products

Product Documents for Melatonin R1A/MT1/MTNR1A Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for Melatonin R1A/MT1/MTNR1A Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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