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Melatonin R1A/MT1/MTNR1A Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-14399

Novus Biologicals, part of Bio-Techne
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NBP3-14399

Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Avian (94%), Canine (94%), Equine (94%), Monkey (94%), Primate (100%). Backed by our 100% Guarantee.

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit

Concentration

1 mg/ml

Product Specifications

Immunogen

Synthetic 16 amino acid peptide from 2nd cytoplasmic domain of human Melatonin R1A/MT1/MTNR1A.

Epitope

Cytoplasmic Domain

Reactivity Notes

Expected reactivity based on percent sequence identity: Marmoset, Mouse, Bovine, Hamster, Xenopus (88%), Rat, Opossum, Lizard (81%)

Specificity

Human Melatonin R1A/MT1/MTNR1A. BLAST analysis of the peptide immunogen showed no homology with other human proteins.

Clonality

Polyclonal

Host

Rabbit

Description

Product can be stored undiluted at 4C for up to 1 month.

Scientific Data Images for Melatonin R1A/MT1/MTNR1A Antibody

Immunohistochemistry-Paraffin: Melatonin R1A/MT1/MTNR1A Antibody [NBP3-14399]

Immunohistochemistry-Paraffin: Melatonin R1A/MT1/MTNR1A Antibody [NBP3-14399]

Immunohistochemistry-Paraffin: Melatonin R1A/MT1/MTNR1A Antibody [NBP3-14399] - Immunohistochemistry of formalin-fixed, paraffin-embedded human brain, neurons and glia, after heat-induced antigen retrieval.
Immunohistochemistry-Paraffin: Melatonin R1A/MT1/MTNR1A Antibody [NBP3-14399]

Immunohistochemistry-Paraffin: Melatonin R1A/MT1/MTNR1A Antibody [NBP3-14399]

Immunohistochemistry-Paraffin: Melatonin R1A/MT1/MTNR1A Antibody [NBP3-14399] - Immunohistochemistry of formalin-fixed, paraffin-embedded human testis
Immunohistochemistry-Paraffin: Melatonin R1A/MT1/MTNR1A Antibody [NBP3-14399]

Immunohistochemistry-Paraffin: Melatonin R1A/MT1/MTNR1A Antibody [NBP3-14399]

Immunohistochemistry-Paraffin: Melatonin R1A/MT1/MTNR1A Antibody [NBP3-14399] - Immunohistochemistry of formalin-fixed, paraffin-embedded human pancreas

Applications for Melatonin R1A/MT1/MTNR1A Antibody

Application
Recommended Usage

Western Blot

0.04-0.4 ug/ml
Application Notes
.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS

Preservative

0.1% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Keep as concentrated solution. Aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.

Background: Melatonin R1A/MT1/MTNR1A

Melatonin Receptor 1A encodes one of two high affinity forms of a receptor for melatonin, the primary hormone secreted by the pineal gland. This receptor is a G-protein coupled, 7-transmembrane receptor that is responsible for melatonin effects on mammalian circadian rhythm and reproductive alterations affected by day length. The receptor is an integral membrane protein that is readily detectable and localized to two specific regions of the brain. The hypothalamic suprachiasmatic nucleus appears to be involved in circadian rhythm while the hypophysial pars tuberalis may be responsible for the reproductive effects of melatonin. [provided by RefSeq]

Long Name

Melatonin Receptor 1A

Alternate Names

Mel-1A-R, MelatoninR1A, MT1, MTNR1A

Gene Symbol

MTNR1A

Additional Melatonin R1A/MT1/MTNR1A Products

Product Documents for Melatonin R1A/MT1/MTNR1A Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for Melatonin R1A/MT1/MTNR1A Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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