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Menin Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-17277

Novus Biologicals, part of Bio-Techne
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NBP2-17277

Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Bovine (98%), Canine (99%), Mouse (97%), Rat (97%). Backed by our 100% Guarantee.

Applications

Immunoprecipitation, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Product Summary for Menin Antibody

Immunogen

Recombinant protein encompassing a sequence within the center region of human Menin. The exact sequence is proprietary.

Localization

Nucleus

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

68 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for Menin Antibody

Western Blot: Menin Antibody [NBP2-17277]

Western Blot: Menin Antibody [NBP2-17277]

Western Blot: Menin Antibody [NBP2-17277] - Sample (30 ug of whole cell lysate) A: Raji 7. 5% SDS PAGE gel, diluted at 1:500.
Immunoprecipitation: Menin Antibody [NBP2-17277]

Immunoprecipitation: Menin Antibody [NBP2-17277]

Immunoprecipitation: Menin Antibody [NBP2-17277] - Immunoprecipitation of MEN1 protein from 293T whole cell extracts using 5 ug of Menin antibody [N1C1]. Western blot analysis was performed using Menin antibody [N1C1]. EasyBlot anti-Rabbit IgG was used as a secondary reagent.

Applications for Menin Antibody

Application
Recommended Usage

Immunoprecipitation

1:100-1:500

Western Blot

1:500-1:3000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Antigen Affinity-purified

Formulation

PBS (pH 7), 20% Glycerol, 1% BSA

Preservative

0.01% Thimerosal

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: Menin

This gene encodes menin, a putative tumor suppressor associated with a syndrome known as multiple endocrine neoplasia type 1. In vitro studies have shown menin is localized to the nucleus, possesses two functional nuclear localization signals, and inhibits transcriptional activation by JunD, however, the function of this protein is not known. Two messages have been detected on northern blots but the larger message has not been characterized. Alternative splicing results in multiple transcript variants. [provided by RefSeq]

Long Name

Multiple Endocrine Neoplasia I

Alternate Names

MEAI, MEN1

Gene Symbol

MEN1

UniProt

Additional Menin Products

Product Documents for Menin Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for Menin Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause reproductive toxicity with developmental effects.  For more information go to www.P65Warnings.ca.gov.