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Meprin alpha Subunit/MEP1A Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-32595

Novus Biologicals, part of Bio-Techne
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NBP1-32595

Key Product Details

Species Reactivity

Validated:

Human

Cited:

Mouse

Applications

Validated:

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Cited:

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Product Specifications

Immunogen

Recombinant protein encompassing a sequence within the center region of human Meprin alpha Subunit/MEP1A. The exact sequence is proprietary.

Reactivity Notes

Mouse reactivity reported in scientific literature (PMID: 23427141). Rat (85%).

Localization

Membrane, Single-pass type I membrane protein

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

84 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for Meprin alpha Subunit/MEP1A Antibody

Western Blot: Meprin alpha Subunit/MEP1A Antibody [NBP1-32595]

Western Blot: Meprin alpha Subunit/MEP1A Antibody [NBP1-32595]

Western Blot: Meprin alpha Subunit/MEP1A Antibody [NBP1-32595] - (30 ug whole cell lysate) A431 7.5% SDS PAGE; antibody diluted at 1:1000

Applications for Meprin alpha Subunit/MEP1A Antibody

Application
Recommended Usage

Western Blot

1:500-1:3000
Application Notes
IHC-P and ICC/IF reactivity reported in scientific literature (PMID: 23427141).

Formulation, Preparation, and Storage

Purification

Antigen Affinity-purified

Formulation

0.1M Tris (pH 7), 0.1M Glycine, 10% Glycerol

Preservative

0.01% Thimerosal

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: Meprin alpha Subunit/MEP1A

Meprins are multidomain zinc metalloproteases that are highly expressed in mammalian kidney and intestinal brush border membranes and in leukocytes and certain cancer cells. Mature meprins are oligomers of evolutionarily related, separately encoded alpha and/or beta subunits. Homooligomers of meprin-alpha are secreted; oligomers containing meprin-beta are associated with the plasma membrane. Substrates include bioactive peptides and extracellular matrix proteins.

Alternate Names

MEP1A, PPHA

Entrez Gene IDs

4224 (Human)

Gene Symbol

MEP1A

UniProt

Additional Meprin alpha Subunit/MEP1A Products

Product Documents for Meprin alpha Subunit/MEP1A Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for Meprin alpha Subunit/MEP1A Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause reproductive toxicity with developmental effects.  For more information go to www.P65Warnings.ca.gov.