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Meprin alpha Subunit/MEP1A Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-87238

Novus Biologicals, part of Bio-Techne
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NBP1-87238
NBP1-87238-25ul

Key Product Details

Validated by

Orthogonal Validation

Species Reactivity

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Product Specifications

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: MSSSMVFTTSKSHTSPAINDTVIWDRPSRVGTYHTDCNCFRSIDLGWSGFISHQMLKRRSFLKNDDLIIFVDFEDITHLSQTEVPTKGKRLSPQGLILQGQEQQVSEEGSGKAMLEEALPVSLSQGQPSRQKRSVE

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Meprin alpha Subunit/MEP1A Antibody

Immunohistochemistry-Paraffin: Meprin alpha Subunit/MEP1A Antibody [NBP1-87238]

Immunohistochemistry-Paraffin: Meprin alpha Subunit/MEP1A Antibody [NBP1-87238]

Immunohistochemistry-Paraffin: Meprin alpha Subunit/MEP1A Antibody [NBP1-87238] - Analysis in human small intestine and liver tissues using Anti-MEP1A antibody. Corresponding MEP1A RNA-seq data are presented for the same tissues.
Immunohistochemistry-Paraffin: Meprin alpha Subunit/MEP1A Antibody [NBP1-87238]

Immunohistochemistry-Paraffin: Meprin alpha Subunit/MEP1A Antibody [NBP1-87238]

Immunohistochemistry-Paraffin: Meprin alpha Subunit/MEP1A Antibody [NBP1-87238] - Staining of human small intestine shows high expression.
Immunohistochemistry-Paraffin: Meprin alpha Subunit/MEP1A Antibody [NBP1-87238]

Immunohistochemistry-Paraffin: Meprin alpha Subunit/MEP1A Antibody [NBP1-87238]

Immunohistochemistry-Paraffin: Meprin alpha Subunit/MEP1A Antibody [NBP1-87238] - Staining of human liver shows low expression as expected.

Applications for Meprin alpha Subunit/MEP1A Antibody

Application
Recommended Usage

Immunohistochemistry

1:50 - 1:200

Immunohistochemistry-Paraffin

1:50 - 1:200
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Meprin alpha Subunit/MEP1A

Meprins are multidomain zinc metalloproteases that are highly expressed in mammalian kidney and intestinal brush border membranes and in leukocytes and certain cancer cells. Mature meprins are oligomers of evolutionarily related, separately encoded alpha and/or beta subunits. Homooligomers of meprin-alpha are secreted; oligomers containing meprin-beta are associated with the plasma membrane. Substrates include bioactive peptides and extracellular matrix proteins.

Alternate Names

MEP1A, PPHA

Gene Symbol

MEP1A

Additional Meprin alpha Subunit/MEP1A Products

Product Documents for Meprin alpha Subunit/MEP1A Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for Meprin alpha Subunit/MEP1A Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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