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Meprin beta Subunit/MEP1B Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-37865

Novus Biologicals, part of Bio-Techne
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NBP2-37865
NBP2-37865-25ul

Key Product Details

Validated by

Orthogonal Validation

Species Reactivity

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Product Specifications

Immunogen

This antibody was developed against a recombinant protein corresponding to amino acids: MTTDNGNYFWDRPSKVGTVALFPNGTQFRRGGGYGTSAFITHERLKSRDFIKGDDVYILLTVEDISHLNSTQIQLTPAPSVQDLCSKTTCKNDGVCTVRDGKAECRC

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Meprin beta Subunit/MEP1B Antibody

Immunohistochemistry-Paraffin: Meprin beta Subunit/MEP1B Antibody [NBP2-37865]

Immunohistochemistry-Paraffin: Meprin beta Subunit/MEP1B Antibody [NBP2-37865]

Immunohistochemistry-Paraffin: Meprin beta Subunit/MEP1B Antibody [NBP2-37865] - Staining in human small intestine and liver tissues using anti-MEP1B antibody. Corresponding MEP1B RNA-seq data are presented for the same tissues.
Immunohistochemistry-Paraffin: Meprin beta Subunit/MEP1B Antibody [NBP2-37865]

Immunohistochemistry-Paraffin: Meprin beta Subunit/MEP1B Antibody [NBP2-37865]

Immunohistochemistry-Paraffin: Meprin beta Subunit/MEP1B Antibody [NBP2-37865] - Staining of human liver shows low expression as expected.
Immunohistochemistry-Paraffin: Meprin beta Subunit/MEP1B Antibody [NBP2-37865]

Immunohistochemistry-Paraffin: Meprin beta Subunit/MEP1B Antibody [NBP2-37865]

Immunohistochemistry-Paraffin: Meprin beta Subunit/MEP1B Antibody [NBP2-37865] - Staining of human small intestine shows high expression.

Applications for Meprin beta Subunit/MEP1B Antibody

Application
Recommended Usage

Immunohistochemistry

1:20 - 1:50

Immunohistochemistry-Paraffin

1:20 - 1:50
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Meprin beta Subunit/MEP1B

Meprins are multidomain zinc metalloproteases that are highly expressed in mammalian kidney and intestinal brush border membranes and in leukocytes and certain cancer cells. Mature meprins are oligomers of evolutionarily related, separately encoded alpha and/or beta subunits. Homooligomers of meprin-alpha are secreted; oligomers containing meprin-beta are associated with the plasma membrane. Substrates include bioactive peptides and extracellular matrix proteins.

Alternate Names

MEP1B

Gene Symbol

MEP1B

UniProt

Additional Meprin beta Subunit/MEP1B Products

Product Documents for Meprin beta Subunit/MEP1B Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for Meprin beta Subunit/MEP1B Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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