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Methionine Aminopeptidase 2/METAP2 Antibody (S07-6C1)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-19889

Recombinant Monoclonal Antibody
Novus Biologicals, part of Bio-Techne
Catalog #
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NBP3-19889-100ul
NBP3-19889-50ul

Key Product Details

Species Reactivity

Validated:

Human, Mouse, Rat

Applications

Western Blot

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # S07-6C1

Concentration

0.3 mg/ml

Product Summary for Methionine Aminopeptidase 2/METAP2 Antibody (S07-6C1)

Immunogen

A synthetic peptide of human Methionine Aminopeptidase 2/METAP2 (Uniprot # P50579)

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

67 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for Methionine Aminopeptidase 2/METAP2 Antibody (S07-6C1)

Western Blot: Methionine Aminopeptidase 2/METAP2 Antibody (S07-6C1) [NBP3-19889]

Western Blot: Methionine Aminopeptidase 2/METAP2 Antibody (S07-6C1) [NBP3-19889]

Western Blot: Methionine Aminopeptidase 2/METAP2 Antibody (S07-6C1) [NBP3-19889] - Western blot detection of Methionine Aminopeptidase 2/METAP2 in A549, HL-60, U251, U87-MG cell lysates using NBP3-19889 (1:1000 diluted). Predicted band size: 53kDa. Observed band size: 67kDa.

Applications for Methionine Aminopeptidase 2/METAP2 Antibody (S07-6C1)

Application
Recommended Usage

Western Blot

1/1000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.05% BSA

Preservative

0.01% Sodium Azide

Concentration

0.3 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Methionine Aminopeptidase 2/METAP2

METAP2 is a member of the methionyl aminopeptidase family and encodes a protein that binds 2 cobalt or manganese ions. This protein functions both by protecting the alpha subunit of eukaryotic initiation factor 2 from inhibitory phosphorylation and by removing the amino-terminal methionine residue from nascent protein. Increased expression of this gene is associated with various forms of cancer and the anti-cancer drugs fumagillin and ovalicin inhibit the protein by irreversibly binding to its active site. A pseudogene of this gene is located on chromosome 2. [provided by RefSeq]

Alternate Names

Amp2, METAP2, MNPEP, p67eIF2

Gene Symbol

METAP2

Additional Methionine Aminopeptidase 2/METAP2 Products

Product Documents for Methionine Aminopeptidase 2/METAP2 Antibody (S07-6C1)

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for Methionine Aminopeptidase 2/METAP2 Antibody (S07-6C1)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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