mGluR2 Antibody (0U6B5)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-16243

Recombinant Monoclonal Antibody
Novus Biologicals, part of Bio-Techne
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NBP3-16243-100ul
NBP3-16243-20ul
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Key Product Details

Species Reactivity

Validated:

Mouse, Rat

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Western Blot

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # 0U6B5

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all mGluR2 Antibodies »

Product Summary for mGluR2 Antibody (0U6B5)

Immunogen

A synthetic peptide corresponding to a sequence within amino acids 773-872 of human mGluR2 (Q14416). WLAFLPIFYVTSSDYRVQTTTMCVSVSLSGSVVLGCLFAPKLHIILFQPQKNVVSHRAPTSRFGSAAARASSSLGQGSGSQFVPTVCNGREVVDSTTSSL

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for mGluR2 Antibody (0U6B5)

Western Blot: mGluR2 Antibody (0U6B5) [NBP3-16243]

Western Blot: mGluR2 Antibody (0U6B5) [NBP3-16243]

Western Blot: mGluR2 Antibody (0U6B5) [NBP3-16243] - Western blot analysis of extracts of various cell lines, using mGluR2 Rabbit mAb (NBP3-16243) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 3min.
Immunohistochemistry: mGluR2 Antibody (0U6B5) [NBP3-16243]

Immunohistochemistry: mGluR2 Antibody (0U6B5) [NBP3-16243]

Immunohistochemistry: mGluR2 Antibody (0U6B5) [NBP3-16243] - Immunofluorescence analysis of mouse brain using mGluR2 Rabbit mAb (NBP3-16243) at dilution of 1:100 (40x lens). Blue: DAPI for nuclear staining.
Immunohistochemistry: mGluR2 Antibody (0U6B5) [NBP3-16243]

Immunohistochemistry: mGluR2 Antibody (0U6B5) [NBP3-16243]

Immunohistochemistry: mGluR2 Antibody (0U6B5) [NBP3-16243] - Immunofluorescence analysis of rat brain using mGluR2 Rabbit mAb (NBP3-16243) at dilution of 1:100 (40x lens). Blue: DAPI for nuclear staining.

Applications for mGluR2 Antibody (0U6B5)

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

1:50 - 1:200

Western Blot

1:500 - 1:1000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS, 0.05% BSA, 50% glycerol, pH7.3

Preservative

0.02% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: mGluR2

The Metabotropic Glutamate Receptor GRM2 binds L-glutamate and has been linked to the inhibition of the cyclic AMP signaling cascade. GRM2 is involved in mediating the suppression of neurotransmission and in synaptogenesis and synaptic stabilization. Glutamatergic neurotransmission plays a role in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. GRM2 has been reported in various regions of the human and animal brain, as well as in rat eye and spinal cord. ESTs have been isolated from brain and testis libraries. Caution: GLUR2 refers to Ionotropic Glutamate Receptor 2, not to Metabotropic Glutamate Receptor 2 (mGLUR2).

Long Name

Metabotropic Glutamate Receptor 2

Alternate Names

GPRC1B, GRM2, mGluR7

Gene Symbol

GRM2

Additional mGluR2 Products

Product Documents for mGluR2 Antibody (0U6B5)

Product Datasheets

Certificate of Analysis

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Product Specific Notices for mGluR2 Antibody (0U6B5)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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