mGluR2 Antibody - BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NLS892

Novus Biologicals, part of Bio-Techne
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NLS892
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Key Product Details

Species Reactivity

Validated:

Human, Mouse, Rat, Porcine, Bat, Bovine, Canine, Hamster, Rabbit

Predicted:

Primate (100%). Backed by our 100% Guarantee.

Applications

Immunocytochemistry, Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free

Concentration

1.0 mg/ml

View all mGluR2 Antibodies »

Product Specifications

Immunogen

Synthetic 19 amino acid peptide from N-terminal extracellular domain of human mGluR2.

Epitope

N-Terminus extracellular domain

Reactivity Notes

Predicted cross-reactivity based on sequence identity: Gorilla (100%), Gibbon (100%), Marmoset (100%).

Localization

Membrane; multi-pass membrane protein

Specificity

Human mGluR2. BLAST analysis of the peptide immunogen showed no homology with other human proteins, except GRM3 (42%).

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Description

Product can be stored undiluted at 4C for up to 1 month.

Scientific Data Images for mGluR2 Antibody - BSA Free

Immunohistochemistry-Paraffin: mGluR2 Antibody - BSA Free [NLS892]

Immunohistochemistry-Paraffin: mGluR2 Antibody - BSA Free [NLS892]

Immunohistochemistry-Paraffin: mGluR2 Antibody [NLS892] - Human Ovary, Carcinoma tissue after heat-induced antigen retrieval.
Immunohistochemistry-Paraffin: mGluR2 Antibody - BSA Free [NLS892]

Immunohistochemistry-Paraffin: mGluR2 Antibody - BSA Free [NLS892]

Immunohistochemistry-Paraffin: mGluR2 Antibody [NLS892] - Analysis of anti-GRM2 / MGLUR2 antibody with brain, neuron.
Immunohistochemistry-Paraffin: mGluR2 Antibody - BSA Free [NLS892]

Immunohistochemistry-Paraffin: mGluR2 Antibody - BSA Free [NLS892]

Immunohistochemistry-Paraffin: mGluR2 Antibody [NLS892] - Analysis of anti-GRM2 / MGLUR2 antibody with transfection control.
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Applications for mGluR2 Antibody - BSA Free

Application
Recommended Usage

Immunocytochemistry

1:10 - 1:500

Immunohistochemistry-Paraffin

5 - 10 ug/ml

Western Blot

1:100 - 1:2000
Application Notes
.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS

Format

BSA Free

Preservative

0.1% Sodium Azide

Concentration

1.0 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Keep as concentrated solution. Aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.

Background: mGluR2

The Metabotropic Glutamate Receptor GRM2 binds L-glutamate and has been linked to the inhibition of the cyclic AMP signaling cascade. GRM2 is involved in mediating the suppression of neurotransmission and in synaptogenesis and synaptic stabilization. Glutamatergic neurotransmission plays a role in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. GRM2 has been reported in various regions of the human and animal brain, as well as in rat eye and spinal cord. ESTs have been isolated from brain and testis libraries. Caution: GLUR2 refers to Ionotropic Glutamate Receptor 2, not to Metabotropic Glutamate Receptor 2 (mGLUR2).

Long Name

Metabotropic Glutamate Receptor 2

Alternate Names

GPRC1B, GRM2, mGluR7

Entrez Gene IDs

2912 (Human)

Gene Symbol

GRM2

Additional mGluR2 Products

Product Documents for mGluR2 Antibody - BSA Free

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for mGluR2 Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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