mGluR3 Antibody - BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NLS3208

Novus Biologicals, part of Bio-Techne
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NLS3208
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Key Product Details

Species Reactivity

Validated:

Human, Porcine, Bovine, Equine, Monkey, Primate

Predicted:

Mouse (94%), Orangutan (100%), Rat (94%). Backed by our 100% Guarantee.

Applications

Immunocytochemistry, Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free

Concentration

1.0 mg/ml

View all mGluR3 Antibodies »

Product Specifications

Immunogen

Synthetic 16 amino acid peptide from N-terminal extracellular domain of human mGluR3.

Epitope

N-terminal extracellular domain of human

Reactivity Notes

Predicted cross-reactivity based on sequence identity: Gorilla (100%), Gibbon (100%), Marmoset (100%), Turkey (81%), Chicken (81%), Xenopus (81%).

Specificity

Human mGluR3. BLAST analysis of the peptide immunogen showed no homology with other human proteins.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Description

Product can be stored undiluted at 4C for up to 1 month.

Scientific Data Images for mGluR3 Antibody - BSA Free

Immunohistochemistry-Paraffin: mGluR3 Antibody - BSA Free [NLS3208]

Immunohistochemistry-Paraffin: mGluR3 Antibody - BSA Free [NLS3208]

Immunohistochemistry-Paraffin: mGluR3 Antibody [NLS3208] - Anti-GRM3 / MGLUR3 antibody IHC of human Brain, Glioblastoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Immunohistochemistry-Paraffin: mGluR3 Antibody - BSA Free [NLS3208]

Immunohistochemistry-Paraffin: mGluR3 Antibody - BSA Free [NLS3208]

Immunohistochemistry-Paraffin: mGluR3 Antibody [NLS3208] - Analysis of anti-GRM3 / MGLUR3 antibody with transfection control.
Immunohistochemistry-Paraffin: mGluR3 Antibody - BSA Free [NLS3208]

Immunohistochemistry-Paraffin: mGluR3 Antibody - BSA Free [NLS3208]

Immunohistochemistry-Paraffin: mGluR3 Antibody [NLS3208] - Analysis of anti-GRM3 / MGLUR3 antibody with HEK293 human embryonic kidney cells transfected with GRM3 / MGLUR3.
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Applications for mGluR3 Antibody - BSA Free

Application
Recommended Usage

Immunocytochemistry

1:10 - 1:500

Immunohistochemistry

5-10 ug/ml

Immunohistochemistry-Paraffin

5-10 ug/ml

Western Blot

1:100 - 1:2000
Application Notes
.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS

Format

BSA Free

Preservative

0.1% Sodium Azide

Concentration

1.0 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Keep as concentrated solution. Aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.

Background: mGluR3

The Metabotropic Glutamate Receptor GRM3 binds L-glutamate, the major excitatory neurotransmitter in the central nervous system, which activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. Metabotropic glutamate receptor Group II includes the GRM2 and GRM3 receptors that are linked to inhibition of the cyclic AMP signaling cascade. GRM3 has been reported in various regions of the brain and spinal cord. ESTs have been isolated from brain, embryo, fetal lung/testis/B-cell, nerve, placenta, prostate, and vessel libraries. Caution: GLUR3 refers to Ionotropic Glutamate Receptor 3, not to Metabotropic Glutamate Receptor 3 (mGLUR3).

Long Name

Metabotropic Glutamate Receptor 3

Alternate Names

GPRC1C, GRM3

Entrez Gene IDs

2913 (Human)

Gene Symbol

GRM3

Additional mGluR3 Products

Product Documents for mGluR3 Antibody - BSA Free

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for mGluR3 Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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