mGluR4 Antibody - BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NLS4713

Novus Biologicals, part of Bio-Techne
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NLS4713
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Key Product Details

Species Reactivity

Validated:

Human, Mouse, Porcine, Monkey, Primate, Rabbit

Predicted:

Chimpanzee (100%), Hamster (94%), Rat (94%). Backed by our 100% Guarantee.

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free

Concentration

1.0 mg/ml

View all mGluR4 Antibodies »

Product Specifications

Immunogen

Synthetic 16 amino acid peptide from C-terminus of human mGluR4.

Epitope

C-Terminus

Reactivity Notes

Predicted cross-reactivity based on sequence identity: Gorilla (100%), Gibbon (100%), Equine (88%), Opossum (88%), Turkey (81%), Chicken (81%).

Specificity

Human mGluR4. BLAST analysis of the peptide immunogen showed no homology with other human proteins.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Description

Product can be stored undiluted at 4C for up to 1 month.

Scientific Data Images for mGluR4 Antibody - BSA Free

Immunohistochemistry-Paraffin: mGluR4 Antibody - BSA Free [NLS4713]

Immunohistochemistry-Paraffin: mGluR4 Antibody - BSA Free [NLS4713]

Immunohistochemistry-Paraffin: mGluR4 Antibody [NLS4713] - Anti-MGLUR4 antibody IHC of human pancreas. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 19 ug/ml.
Immunohistochemistry-Paraffin: mGluR4 Antibody - BSA Free [NLS4713]

Immunohistochemistry-Paraffin: mGluR4 Antibody - BSA Free [NLS4713]

Immunohistochemistry-Paraffin: mGluR4 Antibody [NLS4713] - Analysis of anti-MGLUR4 antibody with human brain, cortex, neurons at dilution 19 ug/ml.

Applications for mGluR4 Antibody - BSA Free

Application
Recommended Usage

Immunohistochemistry-Paraffin

19 ug/ml
Application Notes
.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS

Format

BSA Free

Preservative

0.1% Sodium Azide

Concentration

1.0 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Keep as concentrated solution. Aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.

Background: mGluR4

The Metabotropic Glutamate Receptor mGluR4/GRM4 binds L-glutamate, the major excitatory neurotransmitter in the central nervous system, which activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors that have been divided into 3 groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group III includes GRM4, GRM6, GRM7, and GRM8 receptors that are linked to the inhibition of the cyclic AMP signaling cascade. Two protein isoforms have been reported in rat (mGluR4a 912 aa; mGluRb 983 aa), which differ at the C-terminus. GRM4 has been reported in various regions of the brain, eye, and spinal cord. ESTs have been isolated from brain, embryo, melanocyte/uterus/fetal heart, nerve, and testis libraries. Caution: GLUR4 refers to Ionotropic Glutamate Receptor 4, not to Metabotropic Glutamate Receptor 4 (mGLUR4).

Long Name

Metabotropic Glutamate Receptor 4

Alternate Names

GPRC1D, GRM4

Entrez Gene IDs

2914 (Human)

Gene Symbol

GRM4

Additional mGluR4 Products

Product Documents for mGluR4 Antibody - BSA Free

Product Datasheets

Certificate of Analysis

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Product Specific Notices for mGluR4 Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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