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Mineralocorticoid R/NR3C2 Antibody (PCRP-NR3C2-1E3)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-26819

Novus Biologicals, part of Bio-Techne
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NBP3-26819-100ug
NBP3-26819-20ug

Key Product Details

Species Reactivity

Validated:

Human

Applications

Flow Cytometry

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 Clone # PCRP-NR3C2-1E3

Concentration

0.2 mg/ml

Product Summary for Mineralocorticoid R/NR3C2 Antibody (PCRP-NR3C2-1E3)

Immunogen

Recombinant fragment (around aa601-673) of human Mineralocorticoid R/NR3C2 protein

Localization

Nucleus

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Description

Antibody with azide - store at 2 to 8C. Antibody without azide - store at -20 to -80C. Non-hazardous. No MSDS required.

Scientific Data Images for Mineralocorticoid R/NR3C2 Antibody (PCRP-NR3C2-1E3)

Mineralocorticoid R/NR3C2 Antibody (PCRP-NR3C2-1E3)

Protein Array: Mineralocorticoid R/NR3C2 Antibody (PCRP-NR3C2-1E3) [NBP3-26819 ] -

Analysis of Protein Array containing more than 19,000 full-length human proteins using NR3C2 Mouse Monoclonal (PCRP-NR3C2-1E3).
Mineralocorticoid R/NR3C2 Antibody (PCRP-NR3C2-1E3)

Flow Cytometry: Mineralocorticoid R/NR3C2 Antibody (PCRP-NR3C2-1E3) [NBP3-26819 ] -

Flow Cytometric Analysis of PFA-fixed HeLa cells. Mineralocorticoid R/NR3C2 Antibody (PCRP-NR3C2-1E3) followed by goat anti-mouse IgG-CF488 (blue); unstained cells (red).

Applications for Mineralocorticoid R/NR3C2 Antibody (PCRP-NR3C2-1E3)

Application
Recommended Usage

Flow Cytometry

1-2ug/million cells
Application Notes
Optimal dilution for a specific application should be determined.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A or G purified

Formulation

10mM PBS with 0.05% BSA

Preservative

0.05% Sodium Azide

Concentration

0.2 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C.

Background: Mineralocorticoid R/NR3C2

Steroid receptors are ligand dependent, intracellular proteins that stimulate transcription of specific genes by binding to specific DNA sequences following activation by the appropriate hormone. Mineralocorticoids are a family of steroids, secreted by the adrenal cortex, necessary for the regulation of a number of metabolic processes including electrolyte regulation. These compounds exert their effect through their interaction with the mineralocorticoid receptor and that complex's subsequent association with DNA. Given the function of mineralocorticoids, it is not surprising to find that the kidney is a primary target organ for mineralocorticoids and that this organ has been shown to contain Mineralocorticoid Receptor.

Long Name

Mineralocorticoid Receptor

Alternate Names

MineralocorticoidR, MLR, NR3C2

Gene Symbol

NR3C2

Additional Mineralocorticoid R/NR3C2 Products

Product Documents for Mineralocorticoid R/NR3C2 Antibody (PCRP-NR3C2-1E3)

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for Mineralocorticoid R/NR3C2 Antibody (PCRP-NR3C2-1E3)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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