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MiRP2 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-83238

Novus Biologicals, part of Bio-Techne
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NBP1-83238
NBP1-83238-25ul

Key Product Details

Species Reactivity

Validated:

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Product Summary for MiRP2 Antibody

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: METTNGTETWYESLHAVLKALNATLHSNLLCRPGPGLGPDNQTEERRASLPGRDDN

Reactivity Notes

Immunogen displays the following percentage of sequence identity for non-tested species: Mouse (88%), Rat (80%)

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for MiRP2 Antibody

Immunohistochemistry-Paraffin: MiRP2 Antibody [NBP1-83238]

Immunohistochemistry-Paraffin: MiRP2 Antibody [NBP1-83238]

Immunohistochemistry-Paraffin: MiRP2 Antibody [NBP1-83238] - Staining of human kidney shows strong cytoplasmic positivity in granular pattern in tubule cells.

Applications for MiRP2 Antibody

Application
Recommended Usage

Immunohistochemistry

1:1000 - 1:2500

Immunohistochemistry-Paraffin

1:1000 - 1:2500
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: MiRP2

Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a member of the potassium channel, voltage-gated, isk-related subfamily. This member is a type I membrane protein, and a beta subunit that assembles with a potassium channel alpha-subunit to modulate the gating kinetics and enhance stability of the multimeric complex. This gene is prominently expressed in the kidney. A missense mutation in this gene is associated with hypokalemic periodic paralysis. (provided by RefSeq)

Alternate Names

cardiac voltage-gated potassium channel accessory subunit, DKFZp781H21101, HOKPPMGC102685, HYPP, MGC129924, Minimum potassium ion channel-related peptide 2, MinK-related peptide 2, MiRP2, Potassium channel subunit beta MiRP2, potassium voltage-gated channel subfamily E member 3, potassium voltage-gated channel, Isk-related family, member 3, voltage-gated K+ channel subunit MIRP2

Gene Symbol

KCNE3

Additional MiRP2 Products

Product Documents for MiRP2 Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for MiRP2 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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