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MIS/AMH Antibody (AMH/6713R) [Janelia Fluor® 635]

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-08459JF635

Recombinant Monoclonal Antibody
Novus Biologicals, part of Bio-Techne

Key Product Details

Species Reactivity

Validated:

Human

Applications

Immunohistochemistry-Paraffin

Label

Janelia Fluor 635

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # AMH/6713R

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Product Summary for MIS/AMH Antibody (AMH/6713R) [Janelia Fluor® 635]

Immunogen

A synthetic peptide from the C-terminus of human MIS/AMH (aa 460-560) (exact sequence is proprietary) (Uniprot: IDP03971)

Localization

Secreted

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Applications for MIS/AMH Antibody (AMH/6713R) [Janelia Fluor® 635]

Application
Recommended Usage

Immunohistochemistry-Paraffin

Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Optimal dilution of this antibody should be experimentally determined.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A or G purified

Formulation

50mM Sodium Borate

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: MIS/AMH

Müllerian inhibiting substance (MIS), also named anti-Müllerian hormone (AMH), is a tissue-specific TGF-beta superfamily growth factor. Its expression is restricted to Sertoli cells of fetal and postnatal testis, and to granulosa cells of postnatal ovary. MIS is synthesized and secreted as a disulfide-linked homodimeric propeptide. Proteolytic cleavage is required to separate the N-terminal proregion from the C-terminal bioactive peptide. Both fragments remain associated in a non-covalent complex. The C-terminal sequence forms a cysteine knot via seven canonical cysteine residues found in TGF-beta superfamily members.

Long Name

Mullerian-inhibiting Substance/Anti-Mullerian Hormone

Alternate Names

AMH

Gene Symbol

AMH

Additional MIS/AMH Products

Product Documents for MIS/AMH Antibody (AMH/6713R) [Janelia Fluor® 635]

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for MIS/AMH Antibody (AMH/6713R) [Janelia Fluor® 635]



Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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