MIS RII/AMHR2 Antibody (SR1978)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-22158

Recombinant Monoclonal Antibody
Novus Biologicals, part of Bio-Techne
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NBP3-22158-100ul
NBP3-22158-50ul
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Key Product Details

Species Reactivity

Validated:

Human, Mouse

Applications

Western Blot

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # SR1978

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all MIS RII Antibodies »

Product Summary for MIS RII/AMHR2 Antibody (SR1978)

Immunogen

A synthesized peptide derived from human MIS RII/AMHR2 (Uniprot #: Q16671)

Specificity

Detects endogenous levels of total MIS RII/AMHR2

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

55 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for MIS RII/AMHR2 Antibody (SR1978)

Western Blot: MIS RII/AMHR2 Antibody (SR1978) [NBP3-22158] -

Western Blot: MIS RII/AMHR2 Antibody (SR1978) [NBP3-22158] - Western blot analysis using NBP3-22158 in SK-OV-3 cell lysate.

Applications for MIS RII/AMHR2 Antibody (SR1978)

Application
Recommended Usage

Western Blot

1:500-1:2000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS, pH 7.4, 150mM NaCl, 50% glycerol.

Preservative

0.02% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: MIS RII

AMHR2 is a serine/threonine kinase with a single transmembrane domain belonging to the family of type II receptors for TGF-beta-related proteins that is expressed in fetal and adult gonads of both sexes. Anti-Mullerian hormone (AMH) and its receptor are involved in the regression of Mullerian ducts in male fetuses. Male sex differentiation is mediated by 2 discrete hormones produced by the fetal testis. Testosterone, produced by Leydig cells, virilizes the external genitalia and promotes prostatic growth; anti-Mullerian hormone (AMH) results in regression of Mullerian ducts which would otherwise differentiate into the uterus and fallopian tubes. A number of allelic variants of AMHR2 are associated with persistent mullerian duct syndrome.

Long Name

Mullerian-Inhibiting Substance Type II Receptor

Alternate Names

AMHR2, AMHRII, C14, MISR2, MISRII

Gene Symbol

AMHR2

Additional MIS RII Products

Product Documents for MIS RII/AMHR2 Antibody (SR1978)

Product Datasheets

Certificate of Analysis

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Product Specific Notices for MIS RII/AMHR2 Antibody (SR1978)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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