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Mitochondrial ribosomal protein L11 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-17296

Novus Biologicals, part of Bio-Techne
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NBP2-17296

Key Product Details

Species Reactivity

Validated:

Human, Rat

Predicted:

Rhesus Macaque (98%). Backed by our 100% Guarantee.

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Immunoprecipitation, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Product Specifications

Immunogen

Recombinant protein encompassing a sequence within the center region of human Mitochondrial ribosomal protein L11. The exact sequence is proprietary.

Reactivity Notes

Mouse (89%), Bovine (87%), Rat (81%).

Localization

Mitochondrion

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

21 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for Mitochondrial ribosomal protein L11 Antibody

Western Blot: Mitochondrial ribosomal protein L11 Antibody [NBP2-17296]

Western Blot: Mitochondrial ribosomal protein L11 Antibody [NBP2-17296]

Western Blot: Mitochondrial ribosomal protein L11 Antibody [NBP2-17296] - Various whole cell extracts (30 ug) were separated by 15% SDS-PAGE, and the membrane was blotted with Mitochondrial ribosomal protein L11 Antibody diluted at 1:500. HRP-conjugated anti-rabbit IgG antibody was used to detect the primary antibody.
Immunohistochemistry-Paraffin: Mitochondrial ribosomal protein L11 Antibody [NBP2-17296]

Immunohistochemistry-Paraffin: Mitochondrial ribosomal protein L11 Antibody [NBP2-17296]

Immunohistochemistry-Paraffin: Mitochondrial ribosomal protein L11 Antibody [NBP2-17296] - Paraffin-embedded lung carcinoma. MRPL11 antibody [N1C3] dilution: 1:250.
Western Blot: Mitochondrial ribosomal protein L11 Antibody [NBP2-17296]

Western Blot: Mitochondrial ribosomal protein L11 Antibody [NBP2-17296]

Western Blot: Mitochondrial ribosomal protein L11 Antibody [NBP2-17296] - Sample (30 ug of whole cell lysate) A: A431 12% SDS PAGE gel, diluted at 1:1000.

Applications for Mitochondrial ribosomal protein L11 Antibody

Application
Recommended Usage

Immunohistochemistry

1:100-1:1000

Immunohistochemistry-Paraffin

1:100-1:1000

Immunoprecipitation

1:10 - 1:500

Western Blot

1:500-1:3000

Formulation, Preparation, and Storage

Purification

Antigen Affinity-purified

Formulation

PBS (pH 7), 20% Glycerol, 1% BSA

Preservative

0.01% Thimerosal

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: Mitochondrial ribosomal protein L11

Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. Sequence analysis identified three transcript variants that encode different isoforms. Pseudogenes corresponding to this gene are found on chromosomes 5q and 12q. [provided by RefSeq]

Alternate Names

L11MT, MGC111024, mitochondrial ribosomal protein L11, MRP-L11,39S ribosomal protein L11, mitochondrial

Gene Symbol

MRPL11

UniProt

Additional Mitochondrial ribosomal protein L11 Products

Product Documents for Mitochondrial ribosomal protein L11 Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for Mitochondrial ribosomal protein L11 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause reproductive toxicity with developmental effects.  For more information go to www.P65Warnings.ca.gov.