MLK2 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-87737

Novus Biologicals, part of Bio-Techne
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NBP1-87737
NBP1-87737-25ul
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Key Product Details

Species Reactivity

Validated:

Human, Mouse

Cited:

Mouse

Predicted:

Rat (92%). Backed by our 100% Guarantee.

Applications

Validated:

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Cited:

Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all MLK2 Antibodies »

Product Specifications

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: LPSGFEHKITVQASPTLDKRKGSDGASPPASPSIIPRLRAIRLTPVDCGGSSSGSSSGGSGTWSRGGPPKKEELVGGKKKGRTWGPSSTLQKERVGGEERLKGLGEGSKQWSSS

Reactivity Notes

Mouse reactivity reported in scientific literature (PMID: 30853885).

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for MLK2 Antibody

Immunocytochemistry/ Immunofluorescence: MLK2 Antibody [NBP1-87737]

Immunocytochemistry/ Immunofluorescence: MLK2 Antibody [NBP1-87737]

Immunocytochemistry/Immunofluorescence: MLK2 Antibody [NBP1-87737] - Immunofluorescent staining of human cell line A-431 shows localization to actin filaments.
Immunohistochemistry-Paraffin: MLK2 Antibody [NBP1-87737]

Immunohistochemistry-Paraffin: MLK2 Antibody [NBP1-87737]

Immunohistochemistry-Paraffin: MLK2 Antibody [NBP1-87737] - Staining of human skeletal muscle shows strong cytoplasmic positivity in myocytes.

Applications for MLK2 Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 ug/ml

Immunohistochemistry

1:200 - 1:500

Immunohistochemistry-Paraffin

1:200 - 1:500

Western Blot

0.04-0.4 ug/ml
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended. Immunocytochemistry/Immunofluorescence Fixation Permeabilization: Use PFA/Triton X-100. Use in Western blot reported in scientific literature (PMID: 30853885).

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: MLK2

MLK2, also known as Mitogen-Activated Protein Kinase Kinase Kinase 10, is involved in the induction of apoptosis and the neuronal death mechanism. MLK2 is known to have interactions with ABL2, CLTC, CNKSR1, HTT and KIAA1804. MLK2 has been studied in relation to Alexander disease, Huntington's disease, Parkinson's disease, neuroblastoma, neuronitis, breast carcinoma, and immunodeficiency.

Long Name

Mixed Lineage Kinase 2

Alternate Names

MAP3K10, MST

Entrez Gene IDs

4294 (Human)

Gene Symbol

MAP3K10

UniProt

Q02779 (Human)

Additional MLK2 Products

Product Documents for MLK2 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for MLK2 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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