MMACHC Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-32513

Novus Biologicals, part of Bio-Techne
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NBP1-32513
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Key Product Details

Species Reactivity

Validated:

Human, Mouse, Rat

Predicted:

Bovine (90%). Backed by our 100% Guarantee.

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all MMACHC Antibodies »

Product Specifications

Immunogen

Recombinant protein encompassing a sequence within the center region of human MMACHC. The exact sequence is proprietary.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

32 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for MMACHC Antibody

Western Blot: MMACHC Antibody [NBP1-32513]

Western Blot: MMACHC Antibody [NBP1-32513]

Western Blot: MMACHC Antibody [NBP1-32513] - Whole cell extract (30 ug) was separated by 12% SDS-PAGE, and the membrane was blotted with MMACHC antibody [N1C2] diluted at 1:1000. The HRP-conjugated anti-rabbit IgG antibody (NBP2-19301) was used to detect the primary antibody, and the signal was developed with Trident ECL plus-Enhanced.
Immunocytochemistry/ Immunofluorescence: MMACHC Antibody [NBP1-32513]

Immunocytochemistry/ Immunofluorescence: MMACHC Antibody [NBP1-32513]

Immunocytochemistry/Immunofluorescence: MMACHC Antibody [NBP1-32513] - Paraformaldehyde-fixed HeLa, using antibody at 1:100 dilution.
Immunohistochemistry-Paraffin: MMACHC Antibody [NBP1-32513]

Immunohistochemistry-Paraffin: MMACHC Antibody [NBP1-32513]

Immunohistochemistry-Paraffin: MMACHC Antibody [NBP1-32513] - C2C12 xenograft, using MMACHC antibody at 1:500 dilution. Antigen Retrieval: Trilogy™ (EDTA based, pH 8.0) buffer, 15min.
View 2 more images

Applications for MMACHC Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

1:100-1:1000

Immunohistochemistry

1:100-1:1000

Immunohistochemistry-Paraffin

1:100-1:1000

Western Blot

1:500-1:3000

Formulation, Preparation, and Storage

Purification

Antigen Affinity-purified

Formulation

0.1M Tris-Glycine (pH7), 10% Glycerol

Preservative

0.01% Thimerosal

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: MMACHC

The exact function of the protein encoded by this gene is not known, however, its C-terminal region shows similarity to TonB, a bacterial protein involved in energy transduction for cobalamin (vitamin B12) uptake. Hence, it is postulated that this protein may have a role in the binding and intracellular trafficking of cobalamin. Mutations in this gene are associated with methylmalonic aciduria and homocystinuria type cblC. (provided by RefSeq)

Alternate Names

cblC, DKFZP564I122, FLJ25671, methylmalonic aciduria (cobalamin deficiency) cblC type, with homocystinuria, methylmalonic aciduria and homocystinuria type C protein, RP11-291L19.3

Entrez Gene IDs

25974 (Human); 67096 (Mouse)

Gene Symbol

MMACHC

UniProt

Q9Y4U1 (Human)

Additional MMACHC Products

Product Documents for MMACHC Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for MMACHC Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause reproductive toxicity with developmental effects.  For more information go to www.P65Warnings.ca.gov.

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