MNDA Antibody (OTI4H6)

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-45907

Novus Biologicals, part of Bio-Techne

Key Product Details

Species Reactivity

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG2A Clone # OTI4H6

Concentration

1 mg/ml

View all MNDA Antibodies »

Product Specifications

Immunogen

Human recombinant protein fragment corresponding to amino acids 37-321 of human MNDA(NP_002423) produced in E.coli.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2A

Theoretical MW

45.7 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for MNDA Antibody (OTI4H6)

Western Blot: MNDA Antibody (OTI4H6) [NBP2-45907]

Western Blot: MNDA Antibody (OTI4H6) [NBP2-45907]

Western Blot: MNDA Antibody (4H6) [NBP2-45907] - Analysis of HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY MNDA.
Immunohistochemistry: MNDA Antibody (OTI4H6) [NBP2-45907]

Immunohistochemistry: MNDA Antibody (OTI4H6) [NBP2-45907]

Immunohistochemistry: MNDA Antibody (4H6) [NBP2-45907] - Analysis of Human tonsil tissue. (Heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120C for 3min)
Immunohistochemistry: MNDA Antibody (OTI4H6) [NBP2-45907]

Immunohistochemistry: MNDA Antibody (OTI4H6) [NBP2-45907]

Immunohistochemistry: MNDA Antibody (OTI4H6) [NBP2-45907] - MNDA Antibody (4H6) [NBP2-45907] - Analysis of Adenocarcinoma of Human breast tissue. (Heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120 degrees C for 3min)
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Applications for MNDA Antibody (OTI4H6)

Application
Recommended Usage

Immunohistochemistry

1:150

Immunohistochemistry-Paraffin

1:150

Western Blot

1:2000

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.3), 1.0% BSA and 50% Glycerol

Preservative

0.02% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: MNDA

The myeloid cell nuclear differentiation antigen (MNDA) is detected only in nuclei of cells of the granulocyte-monocyte lineage. A 200-amino acid region of human MNDA is strikingly similar to a region in the proteins encoded by a family of interferon-inducible mouse genes, designated Ifi-201, Ifi-202, and Ifi-203, that are not regulated in a cell- or tissue-specific fashion. The 1.8-kb MNDA mRNA, which contains an interferon-stimulated response element in the 5-prime untranslated region, was significantly upregulated in human monocytes exposed to interferon alpha. MNDA is located within 2,200 kb of FCER1A, APCS, CRP, and SPTA1. In its pattern of expression and/or regulation, MNDA resembles IFI16, suggesting that these genes participate in blood cell-specific responses to interferons.

Alternate Names

myeloid cell nuclear differentiation antigen, PYHIN3

Gene Symbol

MNDA

Additional MNDA Products

Product Documents for MNDA Antibody (OTI4H6)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for MNDA Antibody (OTI4H6)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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