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Mouse IL-31 Antibody

R&D Systems, part of Bio-Techne | Catalog # MAB3028

R&D Systems, part of Bio-Techne
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MAB3028
MAB3028-SP

Key Product Details

Species Reactivity

Mouse

Applications

Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Rat IgG2B Clone # 323407

Product Specifications

Immunogen

E. coli-derived recombinant mouse IL-31
Thr24-Cys163
Accession # Q6EAL8

Specificity

Detects mouse IL-31 in direct ELISAs and Western blots. Does not cross-react with recombinant human IL‑31.

Clonality

Monoclonal

Host

Rat

Isotype

IgG2B

Applications for Mouse IL-31 Antibody

Application
Recommended Usage

Western Blot

1 µg/mL
Sample: Recombinant Mouse IL-31
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A or G purified from hybridoma culture supernatant

Reconstitution

Reconstitute at 0.5 mg/mL in sterile PBS. For liquid material, refer to CoA for concentration.

Reconstitution Buffer Available:
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Formulation

Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.

Shipping

Lyophilized product is shipped at ambient temperature. Liquid small pack size (-SP) is shipped with polar packs. Upon receipt, store immediately at the temperature recommended below.

Stability & Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.

Background: IL-31

IL-31 is a 25 kDa, unique member of the short chain group of alpha-helical cytokines. It is produced by activated T cells, particularly the Th2 CD4+ phenotype. Mouse IL‑31 cDNA encodes a 163 amino acid (aa) precursor that contains a 22 aa signal sequence and a 141 aa mature region. IL-31 signals through a receptor complex composed of IL-31 receptor A and Oncostatin M receptor. Mature mouse IL-31 shares 25% aa sequence identity with mature human IL-31 and 44% aa sequence identity with a rat IL-31-like protein.

Long Name

Interleukin 31

Alternate Names

IL31

Entrez Gene IDs

386653 (Human); 76399 (Mouse)

Gene Symbol

IL31

UniProt

Additional IL-31 Products

Product Documents for Mouse IL-31 Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Note: Certificate of Analysis not available for kit components.

Product Specific Notices for Mouse IL-31 Antibody

For research use only

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