Mouse Serpin I1 Antibody
R&D Systems, part of Bio-Techne | Catalog # AF5054
Key Product Details
Species Reactivity
Mouse
Applications
Western Blot
Label
Unconjugated
Antibody Source
Polyclonal Goat IgG
Product Specifications
Immunogen
Mouse myeloma cell line NS0-derived recombinant mouse Serpin I1
Specificity
Detects mouse Serpin I1 in direct ELISAs and Western blots. In direct ELISAs and Western blots, approximately 50% cross-reactivity with recombinant human (rh) Serpin I1 is observed and less than 5% cross‑reactivity with rhSerpin I2is observed.
Clonality
Polyclonal
Host
Goat
Isotype
IgG
Applications for Mouse Serpin I1 Antibody
Application
Recommended Usage
Western Blot
0.1 µg/mL
Sample: Recombinant Mouse Serpin I1
Sample: Recombinant Mouse Serpin I1
Formulation, Preparation, and Storage
Purification
Antigen Affinity-purified
Reconstitution
Reconstitute at 0.2 mg/mL in sterile PBS. For liquid material, refer to CoA for concentration.
Formulation
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
Shipping
Lyophilized product is shipped at ambient temperature. Liquid small pack size (-SP) is shipped with polar packs. Upon receipt, store immediately at the temperature recommended below.
Stability & Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
- 12 months from date of receipt, -20 to -70 °C as supplied.
- 1 month, 2 to 8 °C under sterile conditions after reconstitution.
- 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Background: Serpin I1
Serpin I1 (serine proteinase inhibitor-clade I 1; also protease inhibitor 17 and neuroserpin) is a 52 kDa member of the serpin superfamily of protease inhibitors. It is a component of dense-core secretory granules in neurons of the cerebellum, hippocampus and hypothalamus and following release shows inhibitory activity towards tissue-type plasminogen activator. The mouse Serpin I1 precursor is 410 amino acids (aa) in length. It contains a 16 aa signal sequence plus a reactive center loop that lies between Gly348 and Pro375. Mature mouse Serpin I1 (aa 17‑410) shares 88% and 92% aa identity with human and rat Serpin I1, respectively.
Alternate Names
Neuroserpin, PI12
Gene Symbol
SERPINI1
Additional Serpin I1 Products
Product Documents for Mouse Serpin I1 Antibody
Product Specific Notices for Mouse Serpin I1 Antibody
For research use only
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