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Mouse TMEFF1/Tomoregulin-1 Biotinylated Antibody

R&D Systems, part of Bio-Techne | Catalog # BAF1995

R&D Systems, part of Bio-Techne
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BAF1995

Key Product Details

Species Reactivity

Mouse

Applications

Immunohistochemistry, Western Blot

Label

Biotin

Antibody Source

Polyclonal Goat IgG

Product Specifications

Immunogen

Mouse myeloma cell line NS0-derived recombinant mouse TMEFF1/Tomoregulin‑1
Ser37-Thr320
Accession # Q6PFE7

Specificity

Detects TMEFF1/Tomoregulin‑1 in Western blots. In Western blots, approximately 40% cross-reactivity with recombinant human (rh) TMEFF1 is observed and less than 2% cross-reactivity with rhTMEFF2 is observed.

Clonality

Polyclonal

Host

Goat

Isotype

IgG

Applications for Mouse TMEFF1/Tomoregulin-1 Biotinylated Antibody

Application
Recommended Usage

Immunohistochemistry

5-15 µg/mL
Sample: Perfusion fixed frozen sections of mouse spinal cord

Western Blot

0.1 µg/mL
Sample: Recombinant Mouse TMEFF1/Tomoregulin-1

Formulation, Preparation, and Storage

Purification

Antigen Affinity-purified

Reconstitution

Reconstitute at 0.2 mg/mL in sterile PBS.

Reconstitution Buffer Available:
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Formulation

Lyophilized from a 0.2 μm filtered solution in PBS with BSA as a carrier protein.

Shipping

The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.

Background: TMEFF1/Tomoregulin-1

TMEFF1, also known as tomoregulin 1 is a type I transmembrane glycoprotein that contains two follistatin modules and an EGF domain in its extracellular domain, a transmembrane domain and a short cytoplasmic tail. The extracellular domain can be released as a soluble protein. TMEFF1 selectively regulates nodal but not activin signaling through direct binding to the nodal co-receptor, Cripto.

Long Name

Transmembrane Protein with EFG-like and two Follistatin-like Domains

Alternate Names

C9orf2, Tomoregulin-1, Tomoregulin1

Entrez Gene IDs

8577 (Human); 230157 (Mouse)

Gene Symbol

TMEFF1

UniProt

Additional TMEFF1/Tomoregulin-1 Products

Product Documents for Mouse TMEFF1/Tomoregulin-1 Biotinylated Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Note: Certificate of Analysis not available for kit components.

Product Specific Notices for Mouse TMEFF1/Tomoregulin-1 Biotinylated Antibody

For research use only

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