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Mouse Urotensin-II R Antibody

R&D Systems, part of Bio-Techne | Catalog # MAB9245

R&D Systems, part of Bio-Techne
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MAB9245-100
MAB9245-SP

Key Product Details

Species Reactivity

Mouse

Applications

CyTOF-ready, Flow Cytometry

Label

Unconjugated

Antibody Source

Monoclonal Rat IgG2B Clone # 443707

Product Specifications

Immunogen

Mouse Urotensin-II R synthetic peptide

Specificity

Detects mouse Urotensin-II R.  Stains mouse Urotensin-II R transfectants but not irrelevant transfectants in flow cytometry.

Clonality

Monoclonal

Host

Rat

Isotype

IgG2B

Scientific Data Images for Mouse Urotensin-II R Antibody

Detection of Urotensin-II R antibody in HEK293 Human Cell Line Transfected with Mouse Urotensin-II and eGFP antibody by Flow Cytometry.

Detection of Urotensin-II R in HEK293 Human Cell Line Transfected with Mouse Urotensin-II and eGFP by Flow Cytometry.

HEK293 human embryonic kidney cell line transfected with either (A) mouse Urotensin-II R or (B) irrelevant transfectants and eGFP was stained with Rat Anti-Mouse Urotensin-II R Monoclonal Antibody (Catalog # MAB9245) followed by Allophycocyanin-conjugated Anti-Rat IgG Secondary Antibody (Catalog # F0113). Quadrant markers were set based on control antibody staining (Catalog # MAB0061). View our protocol for Staining Membrane-associated Proteins.

Applications for Mouse Urotensin-II R Antibody

Application
Recommended Usage

CyTOF-ready

Ready to be labeled using established conjugation methods. No BSA or other carrier proteins that could interfere with conjugation.

Flow Cytometry

0.25 µg/106 cells
Sample: HEK293 human embryonic kidney cell line transfected with mouse Urotensin-II R and eGFP

Formulation, Preparation, and Storage

Purification

Protein A or G purified from hybridoma culture supernatant

Reconstitution

Reconstitute at 0.5 mg/mL in sterile PBS. For liquid material, refer to CoA for concentration.

Reconstitution Buffer Available:
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Formulation

Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.

Shipping

Lyophilized product is shipped at ambient temperature. Liquid small pack size (-SP) is shipped with polar packs. Upon receipt, store immediately at the temperature recommended below.

Stability & Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.

Background: Urotensin-II R

Urotensin-II R (UR2R) belongs to the G protein-coupled receptor 1 family. UR2R is a high affinity receptor for urotensin-2 and urotensin-2B. The activity of UR2R is mediated by a G protein that activates a phosphatidylinositol-calcium second messenger system. It is most abundantly expressed in the heart and pancreas. Human UR2R has been correlated with cortico-adrenal carcinoma proliferation.

Long Name

Urotensin-II Receptor

Alternate Names

GPR14, Urotensin-IIR, UrotensinIIR, UTR, UTR2, UTS2R

Entrez Gene IDs

2837 (Human); 217369 (Mouse); 57305 (Rat)

Gene Symbol

UTS2R

Additional Urotensin-II R Products

Product Documents for Mouse Urotensin-II R Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Note: Certificate of Analysis not available for kit components.

Product Specific Notices for Mouse Urotensin-II R Antibody

For research use only

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