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MP1/MAP2K1IP1 Antibody - BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-81886

Novus Biologicals, part of Bio-Techne

Key Product Details

Species Reactivity

Validated:

Human, Mouse, Rat

Predicted:

Bovine (100%), Chicken (100%). Backed by our 100% Guarantee.

Applications

ELISA, Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free

Concentration

1 mg/ml

Product Specifications

Immunogen

MAP2K1IP1 antibody was raised against an 15 amino acid peptide near the center of human MAP2K1IP1. The immunogen is located within amino acids 40 - 90 of MAP2K1IP1. Amino Acid Squence: ATDQGSKLGLSKNKS

Specificity

MP1/MAP2K1IP1 antibody is human, mouse and rat reactive. At least two isoforms of MP1/MAP2K1IP1 are known to exist; this antibody will detect both isoforms. MP1/MAP2K1IP1 antibody is predicted to not cross-react with other LAMTOR family proteins.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

13 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for MP1/MAP2K1IP1 Antibody - BSA Free

Western Blot: MP1/MAP2K1IP1 AntibodyBSA Free [NBP2-81886]

Western Blot: MP1/MAP2K1IP1 AntibodyBSA Free [NBP2-81886]

Western Blot: MP1/MAP2K1IP1 Antibody [NBP2-81886] - Analysis of MP1/MAP2K1IP1 in human brain tissue lysate with MP1/MAP2K1IP1 antibody at (A) 1 and (B) 2 ug/ml.
Immunocytochemistry/ Immunofluorescence: MP1/MAP2K1IP1 Antibody - BSA Free [NBP2-81886]

Immunocytochemistry/ Immunofluorescence: MP1/MAP2K1IP1 Antibody - BSA Free [NBP2-81886]

Immunocytochemistry/Immunofluorescence: MP1/MAP2K1IP1 Antibody [NBP2-81886] - Analysis of MP1/MAP2K1IP1 in human brain tissue with MP1/MAP2K1IP1 antibody at 20 ug/ml.
Immunohistochemistry: MP1/MAP2K1IP1 Antibody - BSA Free [NBP2-81886]

Immunohistochemistry: MP1/MAP2K1IP1 Antibody - BSA Free [NBP2-81886]

Immunohistochemistry: MP1/MAP2K1IP1 Antibody [NBP2-81886] - Analysis of MP1/MAP2K1IP1 in human brain tissue with MP1/MAP2K1IP1 antibody at 5 ug/ml.

Applications for MP1/MAP2K1IP1 Antibody - BSA Free

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

20 ug/ml

Immunohistochemistry

5 ug/ml

Western Blot

1-2 ug/ml

Formulation, Preparation, and Storage

Purification

Peptide affinity purified

Formulation

PBS

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: MP1

The function of MAP2K1IP1/MAPKSP1 (MP1;MEK partner-1) a 14kDa scaffold protein, is to bind specifically to MEK1 and ERK1 and bring them in close proximity in order to facilitate their activation. Localized to the late endosome, MAP2K1IP1 also interacts with an adaptor protein p14. While the interaction between MAPKSP1-ERK1 can take place in the absence of the adaptor protein p14, it is strengthened in the presence of p14. Additionally, it has been suggested that the binding of MAP2K1IP1/MAPKSP1 to MEK1 resides in a proline-rich sequence (residue 270-307) of MEK1.

Long Name

MEK-binding Protein 1

Alternate Names

LAMTOR3, MAP2K1IP1, Mapbp

Gene Symbol

LAMTOR3

Additional MP1 Products

Product Documents for MP1/MAP2K1IP1 Antibody - BSA Free

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for MP1/MAP2K1IP1 Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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