MPHOSPH1 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-85307

Novus Biologicals, part of Bio-Techne
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NBP2-85307-0.1ml
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Key Product Details

Species Reactivity

Human

Applications

Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit

Concentration

0.5 mg/ml

View all MPHOSPH1 Antibodies »

Product Specifications

Immunogen

The immunogen is a synthetic peptide directed towards the C-terminal region of Human MPHOSPH1. Peptide sequence: DQVLEAKLEEVERLATELEKWKEKCNDLETKNNQRSNKEHENNTDVLGKL The peptide sequence for this immunogen was taken from within the described region.

Clonality

Polyclonal

Host

Rabbit

Scientific Data Images for MPHOSPH1 Antibody

Western Blot: MPHOSPH1 Antibody [NBP2-85307]

Western Blot: MPHOSPH1 Antibody [NBP2-85307]

Western Blot: MPHOSPH1 Antibody [NBP2-85307] - Host: Rabbit. Target Name: KIF20B. Sample Type: 721_B Whole Cell lysates. Antibody Dilution: 1.0ug/ml

Applications for MPHOSPH1 Antibody

Application
Recommended Usage

Western Blot

1.0 ug/ml

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS, 2% Sucrose

Preservative

0.09% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: MPHOSPH1

MPHOSPH1, also known as Kinesin-like protein KIF20B, has 4 isoforms, a 1,820 amino acid isoform that is 211 kDa, a 1,853 amino acid isoform that is 214 kDa, a 1,780 amino acid isoform that is 200 kDa, and a 512 amino acid isoform that is 60 kDa, localizes mainly in the nucleus during interphase although it is also detected in the cytoplasm without clear association with microtubules, it is found in brain, ovary, kidney and testis, and acts as a plus-end-directed motor enzyme that is required for completion of cytokinesis. Disease research is currently being studied with relation to MPHOSPH1 and myeloproliferative disorder, intrahepatic cholangiocarcinoma, cholangiocarcinoma, Alzheimer's disease, and ataxia. This protein involvement has been observed with trelation to MYC, PIN1, RUVBL1, YWHAB, and CDK1proteins in M phase of mitotic cell cycle, ATP catabolic process, microtubule-based movement, cell cycle arrest, and mitosis pathways.

Alternate Names

Cancer/testis antigen 90, CT90MPP-1, DKFZp434B0435, EC 6.3.5.5, kinesin family member 20B, Kinesin-related motor interacting with PIN1, KRMP1kinesin-like protein KIF20B, M-phase phosphoprotein 1mitotic kinesin-like protein, MPHOSPH1EC 2.1.1, MPP1DKFZp434P0810

Gene Symbol

KIF20B

Additional MPHOSPH1 Products

Product Documents for MPHOSPH1 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for MPHOSPH1 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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