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MSH3 Antibody (CL14059)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-24587

Novus Biologicals, part of Bio-Techne
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NBP3-24587-100ul
NBP3-24587-25ul

Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Mouse (100%), Rat (100%). Backed by our 100% Guarantee.

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 Clone # CL14059

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Product Specifications

Immunogen

This antibody was designed to target the recombinant protein MSH3, with the precise immunogen sequence being withheld for proprietary reasons.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Scientific Data Images for MSH3 Antibody (CL14059)

Immunohistochemistry-Paraffin: MSH3 Antibody (CL14059) [NBP3-24587]

Staining of human breast cancer shows moderate to strong nuclear positivity in tumor cells.

Western Blot: MSH3 Antibody (CL14059) [NBP3-24587]

Western blot analysis in human cell line U-251 MG.

Immunohistochemistry-Paraffin: MSH3 Antibody (CL14059) [NBP3-24587]

Staining of human cervix, uterine shows moderate nuclear positivity in squamous epithelial cells.

Applications for MSH3 Antibody (CL14059)

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

2-10 ug/ml

Immunohistochemistry

1:50 - 1:200

Immunohistochemistry-Paraffin

1:50 - 1:200

Western Blot

1ug/ml
Application Notes
ICC/IF, PFA/Triton X-100, IHC-P, Retrieval method: HIER pH6
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

PBS, pH 7.2, 40% glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: MSH3

The function of MSH3 is unknown. It is probably a DNA-repair protein. Defects in MSH3 are a cause of susceptibility to endometrial cancer.

Alternate Names

Divergent upstream protein, DNA mismatch repair protein Msh3, DUC1, DUG, DUPMGC163306, hMSH3, Mismatch repair protein 1, MRP1MGC163308, mutS (E. coli) homolog 3, mutS homolog 3 (E. coli)

Gene Symbol

MSH3

Additional MSH3 Products

Product Documents for MSH3 Antibody (CL14059)

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for MSH3 Antibody (CL14059)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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