MTA1 Antibody (4D5)

Novus Biologicals, part of Bio-Techne | Catalog # H00009112-M01

Novus Biologicals, part of Bio-Techne
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Key Product Details

Species Reactivity

Human, Mouse, Rat

Applications

ELISA, Immunohistochemistry, Immunohistochemistry-Paraffin, Sandwich ELISA, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG3 Kappa Clone # 4D5

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all MTA1 Antibodies »

Product Specifications

Immunogen

MTA1 (NP_004680, 601 a.a. ~ 700 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. MPSRGLANHGQTRHMGPSRNLLLNGKSYPTKVRLIRGGSLPPVKRRRMNWIDAPDDVFYMATEETRKIRKLLSSSETKRAARRPYKPIALRQSQALPPRP

Reactivity Notes

Human, Mouse, & Rat. Other species not tested.

Specificity

MTA1 (4D5)

Clonality

Monoclonal

Host

Mouse

Isotype

IgG3 Kappa

Scientific Data Images for MTA1 Antibody (4D5)

Western Blot: MTA1 Antibody (4D5) [H00009112-M01]

Western Blot: MTA1 Antibody (4D5) [H00009112-M01]

Western Blot: MTA1 Antibody (4D5) [H00009112-M01] - MTA1 monoclonal antibody (M01), clone 4D5 Analysis of MTA1 expression in Hela S3 NE.
Immunohistochemistry-Paraffin: MTA1 Antibody (4D5) [H00009112-M01]

Immunohistochemistry-Paraffin: MTA1 Antibody (4D5) [H00009112-M01]

Immunohistochemistry-Paraffin: MTA1 Antibody (4D5) [H00009112-M01] - Analysis of monoclonal antibody to MTA1 on formalin-fixed paraffin-embedded human esophagus. Antibody concentration 1.2 ug/ml.
Western Blot: MTA1 Antibody (4D5) [H00009112-M01]

Western Blot: MTA1 Antibody (4D5) [H00009112-M01]

Western Blot: MTA1 Antibody (4D5) [H00009112-M01] - MTA1 monoclonal antibody (M01), clone 4D5. Analysis of MTA1 expression in PC-12.
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Applications for MTA1 Antibody (4D5)

Application
Recommended Usage

Western Blot

1:500
Application Notes
Antibody reactive against cell lysate and recombinant protein for western blot. It has also been used for ELISA and immunohistochemistry (paraffin).

Formulation, Preparation, and Storage

Purification

IgG purified

Formulation

In 1x PBS, pH 7.4

Preservative

No Preservative

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: MTA1

This gene encodes a protein that was identified in a screen for genes expressed in metastatic cells, specifically, mammary adenocarcinoma cell lines. Expression of this gene has been correlated with the metastatic potential of at least two types of carcinomas although it is also expressed in many normal tissues. The role it plays in metastasis is unclear. It was initially thought to be the 70kD component of a nucleosome remodeling deacetylase complex, NuRD, but it is more likely that this component is a different but very similar protein. These two proteins are so closely related, though, that they share the same types of domains. These domains include two DNA binding domains, a dimerization domain, and a domain commonly found in proteins that methylate DNA. The profile and activity of this gene product suggest that it is involved in regulating transcription and that this may be accomplished by chromatin remodeling.

Alternate Names

metastasis associated 1, metastasis associated gene 1 protein, metastasis associated protein, metastasis-associated protein MTA1

Entrez Gene IDs

9112 (Human)

Gene Symbol

MTA1

OMIM

603526 (Human)

UniProt

NP_004680 (Human)

Additional MTA1 Products

Product Documents for MTA1 Antibody (4D5)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for MTA1 Antibody (4D5)

This product is produced by and distributed for Abnova, a company based in Taiwan.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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