MTBP Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-19427

Novus Biologicals, part of Bio-Techne
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NBP2-19427
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Key Product Details

Species Reactivity

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all MTBP Antibodies »

Product Specifications

Immunogen

Recombinant protein encompassing a sequence within the center region of human MTBP. The exact sequence is proprietary.

Reactivity Notes

Mouse (81%), Bovine (89%).

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

102 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for MTBP Antibody

Western Blot: MTBP Antibody [NBP2-19427]

Western Blot: MTBP Antibody [NBP2-19427]

Western Blot: MTBP Antibody [NBP2-19427] - Sample (30 ug of whole cell lysate) A: Jurkat B: THP-1 C: HL-60 5% SDS PAGE gel, diluted at 1:1000.
Immunohistochemistry-Paraffin: MTBP Antibody [NBP2-19427]

Immunohistochemistry-Paraffin: MTBP Antibody [NBP2-19427]

Immunohistochemistry-Paraffin: MTBP Antibody [NBP2-19427] - Human colon carcinoma. MTBP antibody [N1N3] dilution: 1:500. Antigen Retrieval: Trilogy™ (EDTA based, pH 8.0) buffer, 15min

Applications for MTBP Antibody

Application
Recommended Usage

Immunohistochemistry

1:100-1:1000

Immunohistochemistry-Paraffin

1:100-1:1000

Western Blot

1:500-1:3000

Formulation, Preparation, and Storage

Purification

Antigen Affinity-purified

Formulation

PBS (pH 7), 20% Glycerol, 1% BSA

Preservative

0.01% Thimerosal

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: MTBP

Inhibits cell migration in vitro and suppresses the invasive behavior of tumor cells (By similarity). May play a role in MDM2-dependent TP53/p53 homeostasis in unstressed cells. Inhibits autoubiquitination of MDM2, thereby enhancing MDM2 stability. This promotes MDM2-mediated ubiquitination of TP53/p53 and its subsequent degradation.

Alternate Names

hMTBP, MDM2 (mouse double minute 2)-binding protein, 104kD, Mdm2, transformed 3T3 cell double minute 2, p53 binding protein (mouse) bindingprotein, 104kDa, mdm2-binding protein, MDM2BP

Gene Symbol

MTBP

UniProt

Q96DY7 (Human)

Additional MTBP Products

Product Documents for MTBP Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for MTBP Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause reproductive toxicity with developmental effects.  For more information go to www.P65Warnings.ca.gov.

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