Mucolipin 1 Antibody
Novus Biologicals, part of Bio-Techne | Catalog # H00057192-B01P
Key Product Details
Species Reactivity
Human
Applications
Western Blot
Label
Unconjugated
Antibody Source
Polyclonal Mouse IgG
Concentration
Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.
Product Specifications
Immunogen
MCOLN1 (NP_065394.1, 1 a.a. - 580 a.a.) full-length human protein. MTAPAGPRGSETERLLTPNPGYGTQAGPSPAPPTPPEEEDLRRRLKYFFMSPCDKFRAKGRKPCKLMLQVVKILVVTVQLILFGLSNQLAVTFREENTIAFRHLFLLGYSDGADDTFAAYTREQLYQAIFHAVDQYLALPDVSLGRYAYVRGGGDPWTNGSGLALCQRYYHRGHVDPANDTFDIDPMVVTDCIQVDPPERPPPPPSDDLTLLESSSSYKNLTLKFHKLVNVTIHFRLKTINLQSLINNEIPDCYTFSVLITFDNKAHSGRIPISLETQAHIQECKHPSVFQHGDNSFRLLFDVVVILTCSLSFLLCARSLLRGFLLQNEFVGFMWRQRGRVISLWERLEFVNGWYILLVTSDVLTISGTIMKIGIEAKNLASYDVCSILLGTSTLLVWVGVIRYLTFFHNYNILIATLRVALPSVMRFCCCVAVIYLGYCFCGWIVLGPYHVKFRSLSMVSECLFSLINGDDMFVTFAAMQAQQGRSSLVWLFSQLYLYSFISLFIYMVLSLFIALITGAYDTIKHPGGAGAEESELQAYIAQCQDSPTSGKFRRGSGSACSLLCCCGRDPSEEHSLLVN
Specificity
Reacts with mucolipin 1.
Clonality
Polyclonal
Host
Mouse
Isotype
IgG
Scientific Data Images for Mucolipin 1 Antibody
![Western Blot: Mucolipin 1 Antibody [H00057192-B01P]](https://resources.bio-techne.com/images/products/Mucolipin-1-Antibody-Western-Blot-H00057192-B01P-img0002.jpg "Western Blot: Mucolipin 1 Antibody [H00057192-B01P]")
Western Blot: Mucolipin 1 Antibody [H00057192-B01P]
Western Blot: Mucolipin 1 Antibody [H00057192-B01P] - Analysis of MCOLN1 expression in transfected 293T cell line by MCOLN1 polyclonal antibody. Lane 1: MCOLN1 transfected lysate(63.8 KDa). Lane 2: Non-transfected lysate.Applications for Mucolipin 1 Antibody
Application
Recommended Usage
Western Blot
Optimal dilutions of this antibody should be experimentally determined.
Application Notes
This antibody is reactive against transfected lysate in western blot, and as a detection antibody in ELISA.
Formulation, Preparation, and Storage
Purification
Protein A purified
Formulation
PBS (pH 7.4)
Preservative
No Preservative
Concentration
Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.
Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Background: Mucolipin 1
Defects in MCOLN1 are known to cause mucolipidosis type IV (MLIV), also known as sialolipidosis. MLIV is an autosomal recessive lysosomal storage disorder characterized by severe psychomotor retardation and ophthalmologic abnormalities, including corneal opacity, retinal degeneration and strabismus. Storage bodies of lipids and water-soluble substances are seen by electron microscopy in almost every cell type of the patients. Most patients are unable to speak or walk independently and reach a maximal developmental level of 1-2 years. All patients have constitutive achlorhydia associated with a secondary elevation of serum gastrin levels.
Long Name
Mucolipin-1
Alternate Names
MCOLN1, MG-2, ML1, ML4, MSTP080, Mucolipidin, TRPML1
Entrez Gene IDs
57192 (Human)
Gene Symbol
MCOLN1
UniProt
Additional Mucolipin 1 Products
Product Documents for Mucolipin 1 Antibody
Product Specific Notices for Mucolipin 1 Antibody
This product is produced by and distributed for Abnova, a company based in Taiwan.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
Loading...
Loading...
Loading...
Loading...