Mucolipin 1 Antibody
Novus Biologicals, part of Bio-Techne | Catalog # NBP3-17197
Key Product Details
Species Reactivity
Validated:
Human
Predicted:
Rat (90%). Backed by our 100% Guarantee.
Applications
Immunocytochemistry/ Immunofluorescence
Label
Unconjugated
Antibody Source
Polyclonal Rabbit IgG
Concentration
Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.
Product Specifications
Immunogen
This antibody was developed against Recombinant Protein corresponding to amino acids: FLLGYSDGADDTFAAYTREQLYQAIFHAVDQYLALPDVSLGRYAYVRGGGDPWTNGSGLALCQRYYHRGHVDPANDTFDIDPMVVTDC
Clonality
Polyclonal
Host
Rabbit
Isotype
IgG
Scientific Data Images for Mucolipin 1 Antibody
![Immunocytochemistry/ Immunofluorescence: Mucolipin 1 Antibody [NBP3-17197]](https://resources.bio-techne.com/images/products/Mucolipin-1-Antibody-Immunocytochemistry-Immunofluorescence-NBP3-17197-img0001.jpg "Immunocytochemistry/ Immunofluorescence: Mucolipin 1 Antibody [NBP3-17197]")
Immunocytochemistry/ Immunofluorescence: Mucolipin 1 Antibody [NBP3-17197]
Immunocytochemistry/Immunofluorescence: Mucolipin 1 Antibody [NBP3-17197] - Staining of human cell line U-2 OS shows localization to nucleoplasm, the Golgi apparatus & vesicles.Applications for Mucolipin 1 Antibody
Application
Recommended Usage
Immunocytochemistry/ Immunofluorescence
0.25-2 ug/ml
Application Notes
Immunocytochemistry/Immunofluorescence, PFA/Triton X-100 is recommended for fixation/permeabilization.
Formulation, Preparation, and Storage
Purification
Affinity purified
Formulation
PBS, pH 7.2, 40% glycerol
Preservative
0.02% Sodium Azide
Concentration
Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.
Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Background: Mucolipin 1
Defects in MCOLN1 are known to cause mucolipidosis type IV (MLIV), also known as sialolipidosis. MLIV is an autosomal recessive lysosomal storage disorder characterized by severe psychomotor retardation and ophthalmologic abnormalities, including corneal opacity, retinal degeneration and strabismus. Storage bodies of lipids and water-soluble substances are seen by electron microscopy in almost every cell type of the patients. Most patients are unable to speak or walk independently and reach a maximal developmental level of 1-2 years. All patients have constitutive achlorhydia associated with a secondary elevation of serum gastrin levels.
Long Name
Mucolipin-1
Alternate Names
MCOLN1, MG-2, ML1, ML4, MSTP080, Mucolipidin, TRPML1
Gene Symbol
MCOLN1
Additional Mucolipin 1 Products
Product Documents for Mucolipin 1 Antibody
Product Specific Notices for Mucolipin 1 Antibody
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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