Mucolipin 3 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-83791

Novus Biologicals, part of Bio-Techne
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NBP1-83791
NBP1-83791-25ul
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Key Product Details

Validated by

Orthogonal Validation

Species Reactivity

Human

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all Mucolipin 3 Antibodies »

Product Specifications

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: YENKGTKQSAMAICQHFYKRGNIYPGNDTFDIDPEIETECFFVEPDEPFHIGTPAENKLNLTLDFHRLLTVELQFKLKAINLQTVRHQELPDCYDFTLT

Reactivity Notes

Immunogen displays the following percentage of sequence identity for non-tested species: Mouse (89%), Rat (87%)

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Mucolipin 3 Antibody

Immunohistochemistry-Paraffin: Mucolipin 3 Antibody [NBP1-83791]

Immunohistochemistry-Paraffin: Mucolipin 3 Antibody [NBP1-83791]

Immunohistochemistry-Paraffin: Mucolipin 3 Antibody [NBP1-83791] - Staining in human adrenal gland and skeletal muscle tissues using anti-MCOLN3 antibody. Corresponding MCOLN3 RNA-seq data are presented for the same tissues.
Immunocytochemistry/ Immunofluorescence: Mucolipin 3 Antibody [NBP1-83791]

Immunocytochemistry/ Immunofluorescence: Mucolipin 3 Antibody [NBP1-83791]

Immunocytochemistry/Immunofluorescence: Mucolipin 3 Antibody [NBP1-83791] - Immunofluorescent staining of human cell line HEK 293 shows localization to nucleoli & cytosol.
Immunohistochemistry-Paraffin: Mucolipin 3 Antibody [NBP1-83791]

Immunohistochemistry-Paraffin: Mucolipin 3 Antibody [NBP1-83791]

Immunohistochemistry-Paraffin: Mucolipin 3 Antibody [NBP1-83791] - Staining of human adrenal gland shows high expression.
View 1 more images

Applications for Mucolipin 3 Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 ug/ml

Immunohistochemistry

1:500 - 1:1000

Immunohistochemistry-Paraffin

1:500 - 1:1000
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended. ICC/IF, Fixation Permeabilization: Use PFA/Triton X-100.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Mucolipin 3

SUBCELLULAR LOCATION: Membrane; Multi-pass membrane protein. TISSUE SPECIFICITY: Expressed in the cochlea; particularly in the inner and outer hair cells. DISEASE: Defects in Mcoln3 are the cause of the varitin-waddler (Va) phenotype. Classical Va mice exhibit early-onset hearing loss, vestibular defects, pigmentation abnormalities and perinatal lethality. The phenotype varitin-waddler Jackcon (Va-J), which arose in a cross segregating for Va, is similar but less severe.

Long Name

Mucolipin-3

Alternate Names

MCOLN3, TRPML3

Gene Symbol

MCOLN3

Additional Mucolipin 3 Products

Product Documents for Mucolipin 3 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for Mucolipin 3 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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