Mus81 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-32474

Novus Biologicals, part of Bio-Techne
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NBP2-32474
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Key Product Details

Species Reactivity

Validated:

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all Mus81 Antibodies »

Product Summary for Mus81 Antibody

Immunogen

This antibody was developed against a recombinant protein corresponding to amino acids: LVEEHGSVHNLSLPESTLLQAVTNTQVIDGFFVKRTADIKESAAYLALLTRGLQRLYQGHTLRSRPWGTPGNPESGAMTSPNPLCSLLTFSDFNAGAIKNKAQSVREVFARQLMQVRGVSGEKAAALVDRYSTPA

Reactivity Notes

Immunogen displays the following percentage of sequence identity for non-tested species: Mouse (89%), Rat (89%)

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Mus81 Antibody

Immunohistochemistry-Paraffin: Mus81 Antibody [NBP2-32474]

Immunohistochemistry-Paraffin: Mus81 Antibody [NBP2-32474]

Immunohistochemistry-Paraffin: Mus81 Antibody [NBP2-32474] - Staining of human esophagus shows moderate nucleolar positivity in squamous epithelial cells.

Applications for Mus81 Antibody

Application
Recommended Usage

Immunohistochemistry

1:50 - 1:200

Immunohistochemistry-Paraffin

1:50 - 1:200
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Mus81

Mus81 and EME1 constitute a heterodimeric endonuclease that has been implicated in mitotic and meiotic recombination in eukaryotes. Reduction or loss of a protein called Mus81 can led to the development of lymphomas and other tumours in mice. Mus81 is a protein long thought to be involved in repairing DNA that is damaged during normal metabolic processes.

Alternate Names

crossover junction endonuclease MUS81, EC 3.1.22, EC 3.1.22.-, FLJ21012, FLJ44872, MUS81 endonuclease homolog (S. cerevisiae), MUS81 endonuclease homolog (yeast), SLX3, SLX3 structure-specific endonuclease subunit homolog

Gene Symbol

MUS81

Additional Mus81 Products

Product Documents for Mus81 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for Mus81 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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