Muscarinic Acetylcholine Receptor M2/CHRM2 Antibody (SR1913)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-22212

Recombinant Monoclonal Antibody
Novus Biologicals, part of Bio-Techne
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NBP3-22212-100ul
NBP3-22212-50ul
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Key Product Details

Species Reactivity

Human, Mouse, Rat

Applications

Immunohistochemistry, Immunoprecipitation, Western Blot

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # SR1913

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all CHRM2 Antibodies »

Product Specifications

Immunogen

A synthesized peptide derived from human Muscarinic Acetylcholine Receptor M2/CHRM2 (Uniprot #: P08172)

Specificity

Detects endogenous levels of total Muscarinic Acetylcholine Receptor M2/CHRM2

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

52 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for Muscarinic Acetylcholine Receptor M2/CHRM2 Antibody (SR1913)

Western Blot: Muscarinic Acetylcholine Receptor M2/CHRM2 Antibody (SR1913) [NBP3-22212] -

Western Blot: Muscarinic Acetylcholine Receptor M2/CHRM2 Antibody (SR1913) [NBP3-22212] - Western blot analysis using NBP3-22212 in U87-MG cell lysate.

Applications for Muscarinic Acetylcholine Receptor M2/CHRM2 Antibody (SR1913)

Application
Recommended Usage

Immunohistochemistry

1:50-1:200

Immunoprecipitation

1:50

Western Blot

1:500-1:2000

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS, pH 7.4, 150mM NaCl, 50% glycerol.

Preservative

0.02% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: CHRM2

Acetylcholine receptors (AChRs) mediate synaptic transmission at the neuromuscular junction. The channel-linked AChR that mediates rapid, excitatory actions of acetylcholine is called nicotinic AChR (nAChR) because it can be activated by nicotine. The non-channel linked AChR that medicates the slow actions of acetylcholine, which can be either inhibitory or excitatory, is called muscarinic AChR (mAChR) because it can be activated by muscarine. The mAChRs are present in neurons of the central and peripheral nervous systems, cardiac and smooth muscle and various exocrine glands. There are 5 subtypes (m1-m5) of the receptor that have a tissue specific pattern of expression. The m2 receptor is localized primarily in cardiac tissue and is also expressed at low levels in the hippocampus, cortex, striatum, thalamus, basal forebrain, brainstem, lung, vas deferens and uterus.

Long Name

Cholinergic Receptor Muscarinic 2

Alternate Names

HM2, mAChR M2

Gene Symbol

CHRM2

Additional CHRM2 Products

Product Documents for Muscarinic Acetylcholine Receptor M2/CHRM2 Antibody (SR1913)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for Muscarinic Acetylcholine Receptor M2/CHRM2 Antibody (SR1913)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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