Muscarinic Acetylcholine Receptor M3/CHRM3 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-56624

Novus Biologicals, part of Bio-Techne
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NBP2-56624
NBP2-56624-25ul
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Key Product Details

Species Reactivity

Validated:

Human

Applications

Immunocytochemistry/ Immunofluorescence

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all CHRM3 Antibodies »

Product Summary for Muscarinic Acetylcholine Receptor M3/CHRM3 Antibody

Immunogen

This antibody was developed against a recombinant protein corresponding to the following amino acid sequence: RCHFWFTTKSWKPSSEQMDQDHSSSDSWNNNDAAASLENSASSDEEDIGSETRAIYSIVLKLPGHSTILNSTKLPSSDNLQVPEEELGMVDLERKADKLQAQKSVDDGGSFPKSFSKLPIQLESAVDTAKTSDVNSSVGK

Reactivity Notes

Mouse 86%, Rat 85%

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Muscarinic Acetylcholine Receptor M3/CHRM3 Antibody

Immunocytochemistry/ Immunofluorescence: Muscarinic Acetylcholine Receptor M3/CHRM3 Antibody [NBP2-56624]

Immunocytochemistry/ Immunofluorescence: Muscarinic Acetylcholine Receptor M3/CHRM3 Antibody [NBP2-56624]

Immunocytochemistry/Immunofluorescence: Muscarinic Acetylcholine Receptor M3/CHRM3 Antibody [NBP2-56624] - Staining of human cell line PC-3 shows localization to plasma membrane. Antibody staining is shown in green.

Applications for Muscarinic Acetylcholine Receptor M3/CHRM3 Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 ug/ml
Application Notes
ICC/IF, Fixation Permeabilization: Use PFA/Triton X-100.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: CHRM3

The muscarinic cholinergic receptors belong to a larger family of G protein-coupled receptors. The functional diversity of these receptors is defined by the binding of acetylcholine and includes cellular responses such as adenylate cyclase inhibition, phosphoinositide degeneration, and potassium channel mediation. Muscarinic receptors influence many effects of acetylcholine in the central and peripheral nervous system. The muscarinic cholinergic receptor 3 controls smooth muscle contraction and its stimulation causes secretion of glandular tissue.

Long Name

Cholinergic Receptor Muscarinic 3

Alternate Names

HM3, mAChR M3

Gene Symbol

CHRM3

Additional CHRM3 Products

Product Documents for Muscarinic Acetylcholine Receptor M3/CHRM3 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for Muscarinic Acetylcholine Receptor M3/CHRM3 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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