Key Product Details

Species Reactivity

Validated:

Human, Mouse, Rat

Cited:

Mouse

Applications

Validated:

ELISA, Immunocytochemistry/ Immunofluorescence, Western Blot

Cited:

Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free

Concentration

1 mg/ml

View all MYBPC1 Antibodies »

Product Specifications

Immunogen

Antibody was raised against an 18 amino acid synthetic peptide near the amino terminus of human MYBPC1. The immunogen is located within amino acids 160 - 210 of MYBPC1. Amino Acid Squence: DIRSAFKRSGEGQEDAGE

Specificity

At least five isoforms of MYBPC1 are known to exist. MYBPC1 antibody is predicted not to cross-react with other MYBPC family members

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for MYBPC1 Antibody - BSA Free

Western Blot: MYBPC1 AntibodyBSA Free [NBP2-41157]

Western Blot: MYBPC1 AntibodyBSA Free [NBP2-41157]

Western Blot: MYBPC1 Antibody [NBP2-41157] - Western blot analysis of MYBPC1 in rat skeletal muscle tissue lysate with MYBPC1 antibody at 1 ug/mL.
Immunocytochemistry/ Immunofluorescence: MYBPC1 Antibody - BSA Free [NBP2-41157]

Immunocytochemistry/ Immunofluorescence: MYBPC1 Antibody - BSA Free [NBP2-41157]

Immunocytochemistry/Immunofluorescence: MYBPC1 Antibody [NBP2-41157] - Immunofluorescence of MYBPC1 in mouse skeletal muscle cells with MYBPC1 antibody at 20 ug/mL.
MYBPC1 Antibody - BSA Free

Immunocytochemistry/ Immunofluorescence: MYBPC1 Antibody - BSA Free [NBP2-41157] -

Immunocytochemistry/ Immunofluorescence: MYBPC1 Antibody - BSA Free [NBP2-41157] - Immunofluorescence of MYBPC1 in mouse skeletal muscle cells with MYBPC1 antibody at 20 u/mL.
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Applications for MYBPC1 Antibody - BSA Free

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

20 ug/mL

Western Blot

1 ug/mL

Formulation, Preparation, and Storage

Purification

Peptide affinity purified

Formulation

PBS

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: MYBPC1

MYBPC1, also known as Myosin-binding protein C, slow-type, is a protein with 10 isoforms ranging from a 1,120 amino acid isoform that is 126 kDa to a 1,173 amino acid isoform that is 131 kDa, located in the crossbridge region of vertebrate striated muscle a bands, plays an important role in muscle contraction by recruiting muscle-type creatine kinase to myosin filaments and modifies the activity of actin-activated myosin ATPase. Studies are being performed on the relationship of this protein to distal arthrogryposis, urethral intrinsic sphincter deficiency, akinetic mutism, hypertrophic cardiomyopathy, familial hypertrophic cardiomyopathy, dilated cardiomyopathy, dysgraphia, laryngeal squamous cell carcinoma, fg syndrome, atrial fibrillation, squamous cell carcinoma, mutism, muscular dystrophy, urethritis, polymyositis, laryngitis, dermatomyositis, myositis, distal arthrogryposis, and urethral intrinsic sphincter deficiency. MYBPC1 protein involvement has been observed with relation to CALM1, CALM2, CALM3, FHL1, MYBPC2, USP25, TTN, DYSF, ACTN2, and more than 30 other proteins in the muscle contraction and striated muscle contraction pathways.

Alternate Names

C-protein, skeletal muscle slow isoform, MYBPCC, MYBPCS, myosin binding protein C, slow type, myosin-binding protein C, slow-type, skeletal muscle C-protein, Slow MyBP-C, slow-type

Gene Symbol

MYBPC1

Additional MYBPC1 Products

Product Documents for MYBPC1 Antibody - BSA Free

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for MYBPC1 Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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