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MYD118 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-87990

Novus Biologicals, part of Bio-Techne
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NBP1-87990
NBP1-87990-25ul

Key Product Details

Species Reactivity

Validated:

Human

Cited:

Human

Predicted:

Mouse (95%), Rat (94%). Backed by our 100% Guarantee.

Applications

Validated:

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin

Cited:

IF/IHC

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Product Specifications

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: AVEELLVAAQRQDRLTVGVYESAKLMNVDPDSVVLCLLAIDEEEEDDIALQIHFTLIQSFCCDNDINIVRVSGMQRLAQLLGEPAETQGTTEARDLHCLLVTNPHTDAWKSHGLVEVASYCEESRGNNQWVPY

Reactivity Notes

Human reactivity reported in scientific literature (PMID: 24708576).

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for MYD118 Antibody

Immunocytochemistry/ Immunofluorescence: MYD118 Antibody [NBP1-87990]

Immunocytochemistry/ Immunofluorescence: MYD118 Antibody [NBP1-87990]

Immunocytochemistry/Immunofluorescence: MYD118 Antibody [NBP1-87990] - Staining of human cell line A-431 shows localization to nucleoplasm & cytosol. Antibody staining is shown in green.
Immunohistochemistry-Paraffin: MYD118 Antibody [NBP1-87990]

Immunohistochemistry-Paraffin: MYD118 Antibody [NBP1-87990]

Immunohistochemistry-Paraffin: MYD118 Antibody [NBP1-87990] - Staining of human skeletal muscle shows weak positivity in a subset of myocytes.
Immunohistochemistry-Paraffin: MYD118 Antibody [NBP1-87990]

Immunohistochemistry-Paraffin: MYD118 Antibody [NBP1-87990]

Immunohistochemistry-Paraffin: MYD118 Antibody [NBP1-87990] - Staining of human placenta shows strong cytoplasmic positivity in trophoblastic cells.

Applications for MYD118 Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 ug/ml

Immunohistochemistry

1:50 - 1:200

Immunohistochemistry-Paraffin

1:50 - 1:200
Application Notes
IHC reported in scientific literature (PMID: 24708576). For IHC-Paraffin, HIER pH 6 retrieval is recommended. ICC/IF Fixation Permeabilization: Use PFA/Triton X-100.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: MYD118

GADD45B is a member of GADD45 family (GADD45®, ®, and ®) that are nuclear proteins to interact with various proteins implicated in stress responses and cell-cycle-related proteins. The function of GADD45 proteins is involved in growth-regulatory mechanisms and apoptosis. GADD45B is necessary for adult neurogenesis, including brain-derived neurotrophic factor and fibroblast growth factor. And therefore, this protein is implicated in affecting synaptic plasticity. Recombinant GADD45B protein was expressed in E.coli and purified by using conventional chromatography techniques.

Alternate Names

DKFZp566B133, GADD45BETA, growth arrest and DNA damage-inducible protein GADD45 beta, growth arrest and DNA-damage-inducible, beta, MYD118DKFZP566B133, Myeloid differentiation primary response protein MyD118, Negative growth regulatory protein MyD118

Gene Symbol

GADD45B

Additional MYD118 Products

Product Documents for MYD118 Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for MYD118 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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