Optimal dilution of this antibody should be experimentally determined. For optimal results using our Tandem dyes, please avoid prolonged exposure to light or extreme temperature fluctuations. These can lead to irreversible degradation or decoupling. When staining intracellular targets, specific attention to the fixation and permeabilization steps in your flow protocol may be required. Please contact our technical support team at technical@novusbio.com if you have any questions.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark. Do not freeze.

Background: MYL7

Myosins are a large family of motor proteins that share the common features of ATP hydrolysis, actin binding andpotential for kinetic energy transduction. Originally isolated from muscle cells (hence the name), almost alleukaryotic cells are now known to contain myosins. Structurally, mysoins contain a head domain that binds to actinfilaments (microfilaments) and is the site of ATP hydrolysis. The tail domain interacts with cargo molecules, and theneck acts as a linker between the head and tail and is the site of regulatory myosin light chain binding. There are 17myosin families and the most well characterized is myosin II. Myosin II is found predominantly in myocytes andmediates plus-ended movement along microfilaments. It is involved in muscle contraction through cyclic interactionswith actin-rich thin filaments, creating a contractile force. It is regulated by phosphorylation via myosin lightchain kinase (MLCK) and by intracellular Ca2+ concentrations.

Alternate Names

atrial isoform, light polypeptide 7, regulatory, MLC-2a, MYL2A, MYLC2AMLC2a, myosin, light chain 7, regulatory

Gene Symbol

MYL7

Additional MYL7 Products

Product Documents for MYL7 Antibody (OTI4E7) [PE/Cy5.5]

Product Datasheets

Download Product Datasheets

COA

SDS

Download SDS

Product Specific Notices for MYL7 Antibody (OTI4E7) [PE/Cy5.5]

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Citations
Reviews

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Flow Cytometry

MYL7 Antibody (OTI4E7) [PE/Cy5.5]

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-72859PECY55

Key Product Details

Species Reactivity

Applications

Label

Antibody Source

Concentration

View all MYL7 Antibodies »

Product Specifications

Immunogen

Clonality

Host

Isotype

Applications for MYL7 Antibody (OTI4E7) [PE/Cy5.5]

Flow Cytometry

Immunohistochemistry

Immunohistochemistry-Paraffin

Western Blot

Formulation, Preparation, and Storage

Purification

Formulation

Preservative

Concentration

Shipping

Stability & Storage

Background: MYL7

Alternate Names

Gene Symbol

Additional MYL7 Products

Product Documents for MYL7 Antibody (OTI4E7) [PE/Cy5.5]

Product Datasheets

COA

Certificate of Analysis

SDS

Product Specific Notices for MYL7 Antibody (OTI4E7) [PE/Cy5.5]

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