MYO18A Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NB100-79839

Novus Biologicals, part of Bio-Techne
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NB100-79839
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Key Product Details

Validated by

Independent Antibodies

Species Reactivity

Human

Applications

Immunoprecipitation

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

1.0 mg/ml

View all MYO18A Antibodies »

Product Specifications

Immunogen

The immunogen this antibody was made to, maps to a region between residue 300 and 350 of human myosin 18A using the numbering given in entry NP_510880.2 (GeneID 399687).

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for MYO18A Antibody

Immunoprecipitation: MYO18A Antibody [NB100-79839]

Immunoprecipitation: MYO18A Antibody [NB100-79839]

Immunoprecipitation: MYO18A Antibody [NB100-79839] - Detection of Human Myo18A/Myosin XVIIIA by Western Blot of Immunoprecipitates. Samples: RIPA whole cell lysate (1 mg for IP, 20% of IP loaded) from HeLa cells. Antibodies: Affinity purified rabbit anti-Myo18A/Myosin XVIIIA antibody NB100-79839 used for IP at 3 mcg/mg lysate. Myo18A/Myosin XVIIIA was also immunoprecipitated by rabbit anti- Myo18A/Myosin XVIIIA antibody NB100-79840, which recognizes a downstream epitope. Detection: Chemiluminescence with an exposure time of 1 second.

Applications for MYO18A Antibody

Application
Recommended Usage

Immunoprecipitation

2-5 mcg/mg lysate
Application Notes
This antibody has not performed satisfactorily when used for WB of Myo18A/Myosin XVIIIA in crude preparations (e.g. whole cell lysate). This antibody can be used for WB of enriched (e.g. immunoprecipitated) sources of Myo18A/Myosin XVIIIA.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

Tris-Citrate/Phosphate (pH 7.0 - 8.0)

Preservative

0.09% Sodium Azide

Concentration

1.0 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C. Do not freeze.

Background: MYO18A

Myo18A/Myosin XVIIIA is an unconventional myosin that contains a lysine and glutamine (KE)-rich domain and a PDZ domain. The KE and PDZ domains appear to direct subcellular localization of the Myo18A variants. It is a dimeric actin binding protein that may play a role in the stabilization and organization of the actin cytoskeleton. Recently a cell surface form of Myo18A has been identified as the receptor for surfactant protein A, a lipid-associated lung collectin that mediates innate and adaptive immune responses in the lungs.

Alternate Names

KIAA0216DKFZp686L0243, MAJN, Molecule associated with JAK3 N-terminus, myosin 18A, Myosin containing a PDZ domain, myosin containing PDZ domain, myosin XVIIIA, myosin-XVIIIa, MysPDZ, SP-A receptor subunit SP-R210 alphaS, SPR210

Entrez Gene IDs

399687 (Human)

Gene Symbol

MYO18A

UniProt

NP_510880.2 (Human)

Additional MYO18A Products

Product Documents for MYO18A Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for MYO18A Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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