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Myosin Heavy Chain 1 Antibody (MY32)

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-22811

Novus Biologicals, part of Bio-Techne
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NBP1-22811

Key Product Details

Species Reactivity

Human, Rabbit

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Simple Western

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 Clone # MY32

Concentration

This product is unpurified. The exact concentration of antibody is not quantifiable.

Product Specifications

Immunogen

Rabbit muscle myosin.

Localization

Cytoplasmic

Specificity

This antibody recognizes the heavy chain of human skeletal myosin. It does not stain cardiac or smooth muscle myosin. Rather, it stains the fast twitch (type II) isomyosin molecule.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Description

This product has a prediluted size available. If a 6mL or 7mL pre-diluted size is purchased this product can be used Neat (without further dilution). Use recommended dilution for the concentrated vials only.

Scientific Data Images for Myosin Heavy Chain 1 Antibody (MY32)

Immunohistochemistry-Paraffin: Myosin Heavy Chain 1 Antibody (MY32) [NBP1-22811]

Immunohistochemistry-Paraffin: Myosin Heavy Chain 1 Antibody (MY32) [NBP1-22811]

Immunohistochemistry-Paraffin: Myosin Heavy Chain 1 Antibody (MY32) [NBP1-22811] - Formalin fixed paraffin embedded human skeletal muscle stained with Myosin Heavy Chain 1 antibody (NBP1-22811).

Applications for Myosin Heavy Chain 1 Antibody (MY32)

Application
Recommended Usage

Immunohistochemistry

1:10-1:500
Application Notes
IHC-P: recommended pretreatment of citrate buffer, pH 6.0. Recommended incubation time of 30 min at RT.

Formulation, Preparation, and Storage

Purification

Ascites

Formulation

Ascites

Preservative

0.05% Sodium Azide

Concentration

This product is unpurified. The exact concentration of antibody is not quantifiable.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C.

Background: Myosin Heavy Chain 1/MYH1

Myosin II is the so called "classical" myosin, being the first type of myosin to be discovered. Myosin II forms bipolar filaments that interact with actin filaments to produce contraction. Myosin II was first isolated from muscle but is also found in non muscle cells, and it is especially enriched in highly motile cell types such as amoebae. The myosin II molecule is composed of two heavy chains and two sets of light chains. The light chains are the Essential Light Chains (ELC) and Regulatory Light Chains (RLC). Overall activity and polymerization can be modulated by phosphorylation on the light chains and the C terminus of the heavy chains respectively.

Long Name

Myosin Heavy Chain 1

Alternate Names

MGC133384, MYH1, MyHC-2x, MyHC-IIx/d, Myosin-1

Gene Symbol

MYH1

Additional Myosin Heavy Chain 1/MYH1 Products

Product Documents for Myosin Heavy Chain 1 Antibody (MY32)

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for Myosin Heavy Chain 1 Antibody (MY32)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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