Myosin heavy chain 11 Antibody (MYH11/923) - IHC-Prediluted
Novus Biologicals, part of Bio-Techne | Catalog # NBP2-48149
![Immunohistochemistry-Paraffin: Myosin heavy chain 11 Antibody (MYH11/923) - IHC-Prediluted [NBP2-48149]](https://resources.bio-techne.com/images/products/Myosin-heavy-chain-11-Antibody-MYH11-923-IHC-Prediluted-Immunohistochemistry-Paraffin-NBP2-48149-img0003.jpg "Immunohistochemistry-Paraffin: Myosin heavy chain 11 Antibody (MYH11/923) - IHC-Prediluted [NBP2-48149]")
![Immunohistochemistry-Paraffin: Myosin heavy chain 11 Antibody (MYH11/923) - IHC-Prediluted [NBP2-48149]](https://resources.bio-techne.com/images/products/Myosin-heavy-chain-11-Antibody-MYH11-923-IHC-Prediluted-Immunohistochemistry-Paraffin-NBP2-48149-img0004.jpg "Immunohistochemistry-Paraffin: Myosin heavy chain 11 Antibody (MYH11/923) - IHC-Prediluted [NBP2-48149]")
Conjugate
Catalog #
Forumulation
Catalog #
Key Product Details
Species Reactivity
Validated:
Human, Rat
Applications
Immunohistochemistry, Immunohistochemistry-Paraffin
Label
Unconjugated
Antibody Source
Monoclonal Mouse IgG1 kappa Clone # MYH11/923
Format
IHC-Prediluted
Concentration
Please see the vial label for concentration. If unlisted please contact technical services.
Product Summary for Myosin heavy chain 11 Antibody (MYH11/923) - IHC-Prediluted
Immunogen
Recombinant full-length human Myosin heavy chain 11 protein (Uniprot: P35749)
Reactivity Notes
Predicted to have broad species reactivity.
Localization
Cytoplasmic
Specificity
Smooth muscle myosin heavy chain (SM-MHC) is a cytoplasmic structural protein, which is a major component of the contractile apparatus in smooth muscle cells. Expression of smooth muscle myosin is developmentally regulated, appearing early in smooth muscle development, and is specific for smooth muscle development. Two isoforms of smooth muscle myosin heavy chain have been identified, designated MHC-1 and MHC-2. The antibody may be useful for the study of breast tumors as the presence of an intact layer of myoepithelial cells is an important feature, which may distinguish benign breast lesions and carcinoma in situ from invasive tumors.
Marker
Leiomyosarcoma & Myoepithelial Cell Marker
Clonality
Monoclonal
Host
Mouse
Isotype
IgG1 kappa
Description
The prediluted antibody does not require any mixing, dilution, reconstitution, or titration; the antibody is ready-to-use and optimized for staining.
Scientific Data Images for Myosin heavy chain 11 Antibody (MYH11/923) - IHC-Prediluted
Immunohistochemistry-Paraffin: Myosin heavy chain 11 Antibody (MYH11/923) - IHC-Prediluted [NBP2-48149]
Immunohistochemistry-Paraffin: Myosin heavy chain 11 Antibody (MYH11/923) - IHC-Prediluted [NBP2-48149] - Human Angiosarcoma stained with SM-MHC Mouse Monoclonal Antibody (MYH11/923).![Immunohistochemistry-Paraffin: Myosin heavy chain 11 Antibody (MYH11/923) - IHC-Prediluted [NBP2-48149]](https://resources.bio-techne.com/images/products/Myosin-heavy-chain-11-Antibody-MYH11-923-IHC-Prediluted-Immunohistochemistry-Paraffin-NBP2-48149-img0001.jpg "Immunohistochemistry-Paraffin: Myosin heavy chain 11 Antibody (MYH11/923) - IHC-Prediluted [NBP2-48149]")
Immunohistochemistry-Paraffin: Myosin heavy chain 11 Antibody (MYH11/923) - IHC-Prediluted [NBP2-48149]
Immunohistochemistry-Paraffin: Myosin heavy chain 11 Antibody (MYH11/923) - IHC-Prediluted [NBP2-48149] - Human Breast Carcinoma stained with SM-MHC Mouse Monoclonal Antibody (MYH11/923).![Immunohistochemistry-Paraffin: Myosin heavy chain 11 Antibody (MYH11/923) - IHC-Prediluted [NBP2-48149]](https://resources.bio-techne.com/images/products/Myosin-heavy-chain-11-Antibody-MYH11-923-IHC-Prediluted-Immunohistochemistry-Paraffin-NBP2-48149-img0002.jpg "Immunohistochemistry-Paraffin: Myosin heavy chain 11 Antibody (MYH11/923) - IHC-Prediluted [NBP2-48149]")
Immunohistochemistry-Paraffin: Myosin heavy chain 11 Antibody (MYH11/923) - IHC-Prediluted [NBP2-48149]
Immunohistochemistry-Paraffin: Myosin heavy chain 11 Antibody (MYH11/923) - IHC-Prediluted [NBP2-48149] - Human Leiomyosarcoma stained with SM-MHC Mouse Monoclonal Antibody (MYH11/923).Applications for Myosin heavy chain 11 Antibody (MYH11/923) - IHC-Prediluted
Application
Recommended Usage
Immunohistochemistry
Optimal dilutions of this antibody should be experimentally determined.
Immunohistochemistry-Paraffin
Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Immunohistochemistry (Formalin-fixed): 1-2ug/ml for 30 minutes at RT. Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95C followed by cooling at RT for 20 minutes.
Optimal dilution for a specific application should be determined.
Optimal dilution for a specific application should be determined.
Please Note: Optimal dilutions of this antibody should be experimentally determined.
Formulation, Preparation, and Storage
Purification
Protein A or G purified
Formulation
10 mM PBS with 0.05% BSA
Format
IHC-Prediluted
Preservative
0.05% Sodium Azide
Concentration
Please see the vial label for concentration. If unlisted please contact technical services.
Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Store at 4C.
Background: Myosin heavy chain 11
Alternate Names
AAT4, FAA4, MYH11, MYH11 myosin, heavy chain 11, smooth muscle, SMHC, SMMHC, Smooth muscle myosin heavy chain
Gene Symbol
MYH11
Additional Myosin heavy chain 11 Products
Product Documents for Myosin heavy chain 11 Antibody (MYH11/923) - IHC-Prediluted
Product Specific Notices for Myosin heavy chain 11 Antibody (MYH11/923) - IHC-Prediluted
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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