Myosin heavy chain 2 Antibody (TH81 (BGN/04/4481)) - BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NB100-65675

Novus Biologicals, part of Bio-Techne
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NB100-65675-0.025mg
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Key Product Details

Species Reactivity

Human, Rat, Rabbit

Applications

Validated:

ELISA, Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin

Cited:

Immunocytochemistry/ Immunofluorescence

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 Clone # TH81 (BGN/04/4481)

Format

BSA Free

Concentration

1.0 mg/ml

View all Myosin heavy chain 2/MYH2 Antibodies »

Product Specifications

Immunogen

Myosin heavy chain from rabbit muscle

Localization

Cytoplasm, myofibril. Note: thick filaments of the myofibrils.

Specificity

NB100-65675 reacts strongly with human cardiac myosin and also recognizes rabbit myosin heavy and light chains.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Applications for Myosin heavy chain 2 Antibody (TH81 (BGN/04/4481)) - BSA Free

Application
Recommended Usage

ELISA

1:100-1:2000

Immunocytochemistry/ Immunofluorescence

1:10-1:500

Immunohistochemistry

1:10-1:500

Immunohistochemistry-Paraffin

1:10-1:500

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

PBS (pH 7.2)

Format

BSA Free

Preservative

0.09% Sodium Azide

Concentration

1.0 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Myosin heavy chain 2/MYH2

Myosin II is the so called "classical" myosin, being the first type of myosin to be discovered. Myosin II forms bipolar filaments that interact with actin filaments to produce contraction. Myosin II was first isolated from muscle but is also found in non muscle cells, and it is especially enriched in highly motile cell types such as amoebae. The myosin II molecule is composed of two heavy chains and two sets of light chains. The light chains are the Essential Light Chains (ELC) and Regulatory Light Chains (RLC). Overall activity and polymerization can be modulated by phosphorylation on the light chains and the C terminus of the heavy chains respectively.

Long Name

Myosin Heavy Chain 2

Alternate Names

IBM3, MYH2, MyHC-2a, MyHC-IIa, MYHSA2

Entrez Gene IDs

4620 (Human)

Gene Symbol

MYH2

Additional Myosin heavy chain 2/MYH2 Products

Product Documents for Myosin heavy chain 2 Antibody (TH81 (BGN/04/4481)) - BSA Free

Product Datasheets

Certificate of Analysis

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Product Specific Notices for Myosin heavy chain 2 Antibody (TH81 (BGN/04/4481)) - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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