Myosin VIIa Antibody (SR1387)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-21878

Recombinant Monoclonal Antibody
Novus Biologicals, part of Bio-Techne
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NBP3-21878-100ul
NBP3-21878-50ul
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Key Product Details

Species Reactivity

Human, Mouse, Rat

Applications

Flow Cytometry, Immunocytochemistry/ Immunofluorescence, Western Blot

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # SR1387

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all Myosin VIIa Antibodies »

Product Specifications

Immunogen

A synthesized peptide derived from human Myosin VIIa (Uniprot #: Q13402)

Specificity

Detects endogenous levels of total Myosin VIIa

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

254 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for Myosin VIIa Antibody (SR1387)

Western Blot: Myosin VIIa Antibody (SR1387) [NBP3-21878] -

Western Blot: Myosin VIIa Antibody (SR1387) [NBP3-21878] - Western blot analysis using NBP3-21878 in Y79 cell lysate.

Applications for Myosin VIIa Antibody (SR1387)

Application
Recommended Usage

Flow Cytometry

1:100

Immunocytochemistry/ Immunofluorescence

1:50-1:200

Western Blot

1:500-1:2000

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS, pH 7.4, 150mM NaCl, 50% glycerol.

Preservative

0.02% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Myosin VIIa

Myosin VIIa is a member of the myosin superfamily of actin-based motor proteins. Defects in the myosin VIIa gene are responsible for hearing impairment in shaker-1 (sh1) mice and causes Usher syndrome IB in humans. Usher syndrome associates congenital deafness, vestibular dysfunction, and retinitis pigmentosa and is the most common form of combined deafness and blindness. Structural features of myosin VIIa protein include an ATP binding N-terminal motor domain, a central region which possess five light-chain binding (IQ) motifs, and a C-terminal domain with three myosin tail homology (MyTH4) and talin-like homology regions.

Alternate Names

deafness, autosomal dominant 11, deafness, autosomal recessive 2, DFNA11, DFNB2, myosin VIIA, myosin-VIIa, MYOVIIA, MYU7A, USH1Bsevere))

Gene Symbol

MYO7A

Additional Myosin VIIa Products

Product Documents for Myosin VIIa Antibody (SR1387)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for Myosin VIIa Antibody (SR1387)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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