Myotilin Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-38361

Novus Biologicals, part of Bio-Techne
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NBP2-38361
NBP2-38361-25ul
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Key Product Details

Validated by

Orthogonal Validation, Independent Antibodies

Species Reactivity

Validated:

Human

Predicted:

Mouse (93%), Rat (95%). Backed by our 100% Guarantee.

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all Myotilin Antibodies »

Product Summary for Myotilin Antibody

Immunogen

This antibody was developed against a recombinant protein corresponding to amino acids: ACVAKNRAGEATFTVQLDVLAKEHKRAPMFIYKPQSKKVLEGDSVKLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAG

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Myotilin Antibody

Immunohistochemistry-Paraffin: Myotilin Antibody [NBP2-38361]

Immunohistochemistry-Paraffin: Myotilin Antibody [NBP2-38361]

Immunohistochemistry-Paraffin: Myotilin Antibody [NBP2-38361] - Staining of human testis.
Immunohistochemistry-Paraffin: Myotilin Antibody [NBP2-38361]

Immunohistochemistry-Paraffin: Myotilin Antibody [NBP2-38361]

Immunohistochemistry-Paraffin: Myotilin Antibody [NBP2-38361] - Staining of human skeletal muscle shows high expression.
Immunohistochemistry-Paraffin: Myotilin Antibody [NBP2-38361]

Immunohistochemistry-Paraffin: Myotilin Antibody [NBP2-38361]

Immunohistochemistry-Paraffin: Myotilin Antibody [NBP2-38361] - Staining of human skin shows low expression as expected.
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Applications for Myotilin Antibody

Application
Recommended Usage

Immunohistochemistry

1:50 - 1:200

Immunohistochemistry-Paraffin

1:50 - 1:200
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Myotilin

Striated muscle sarcomeres are highly organized structures composed of actin (thin) and myosin (thick) filaments that slide past each other during contraction. The integrity of sarcomeres is controlled by a set of structural proteins, among which are titin (TTN; MIM 188840), a giant molecule that contains several immunoglobulin (Ig)-like domains and associates with thin and thick filaments, and alpha-actinin (ACTN1; MIM 102575), an actin cross-linking protein. Mutations in several sarcomeric and sarcolemmal proteins have been shown to result in muscular dystrophy and cardiomyopathy.[supplied by OMIM]

Alternate Names

57 kDa cytoskeletal protein, LGMD1A, limb-girdle muscular dystrophy 1A (autosomal dominant), Myofibrillar titin-like Ig domains protein, myotilin, Titin immunoglobulin domain protein, titin immunoglobulin domain protein (myotilin), TTIDLGMD1

Gene Symbol

MYOT

UniProt

Q9UBF9 (Human)

Additional Myotilin Products

Product Documents for Myotilin Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for Myotilin Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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