N-Deacetylase/N-Sulfotransferase 1/NDST1 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-37978

Novus Biologicals, part of Bio-Techne
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NBP2-37978
NBP2-37978-25ul
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Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Mouse (100%), Rat (100%). Backed by our 100% Guarantee.

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all N-Deacetylase/N-Sulfotransferase 1/NDST1 Antibodies »

Product Summary for N-Deacetylase/N-Sulfotransferase 1/NDST1 Antibody

Immunogen

This antibody was developed against a recombinant protein corresponding to amino acids: YEPVLLAKTRSSESIPHLGADAGLHAALHATVVQ

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for N-Deacetylase/N-Sulfotransferase 1/NDST1 Antibody

Immunohistochemistry-Paraffin: N-Deacetylase/N-Sulfotransferase 1/NDST1 Antibody [NBP2-37978]

Immunohistochemistry-Paraffin: N-Deacetylase/N-Sulfotransferase 1/NDST1 Antibody [NBP2-37978]

Immunohistochemistry-Paraffin: N-Deacetylase/N-Sulfotransferase 1/NDST1 Antibody [NBP2-37978] - Staining of human liver shows strong cytoplasmic positivity in hepatocytes.

Applications for N-Deacetylase/N-Sulfotransferase 1/NDST1 Antibody

Application
Recommended Usage

Immunohistochemistry

1:1000 - 1:2500

Immunohistochemistry-Paraffin

1:1000 - 1:2500
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: N-Deacetylase/N-Sulfotransferase 1/NDST1

Essential bifunctional enzyme that catalyzes both the N-deacetylation and the N-sulfation of glucosamine(GlcNAc) of the glycosaminoglycan in heparan sulfate. Modifies the GlcNAc-GlcA dissacharide repeating sugar backboneto make N-sulfated heparosan, a prerequisite substrate for later modifications in heparin biosynthesis. Plays a rolein determining the extent and pattern of sulfation of heparan sulfate. Compared to other NDST enzymes, its presence isabsolutely required. Participates in biosynthesis of heparan sulfate that can ultimately serve as L-selectin ligands,thereby playing a role in inflammatory response

Alternate Names

HSNST1, HSST1, NST1

Gene Symbol

NDST1

UniProt

P52848

Additional N-Deacetylase/N-Sulfotransferase 1/NDST1 Products

Product Documents for N-Deacetylase/N-Sulfotransferase 1/NDST1 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for N-Deacetylase/N-Sulfotransferase 1/NDST1 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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