N-PAC Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-38618

Novus Biologicals, part of Bio-Techne
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NBP2-38618
NBP2-38618-25ul
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Key Product Details

Validated by

Independent Antibodies

Species Reactivity

Validated:

Human

Predicted:

Mouse (100%), Rat (100%). Backed by our 100% Guarantee.

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all N-PAC Antibodies »

Product Specifications

Immunogen

This antibody was developed against a recombinant protein corresponding to amino acids: KCYVDMSTVDADTVTELAQVIVSRGGRFLEAPVSGNQQLSNDGMLVILAAGDRGLYEDCSSCFQAMGKTSFFLGEVGNAAKMMLIV

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for N-PAC Antibody

Immunocytochemistry/ Immunofluorescence: N-PAC Antibody [NBP2-38618]

Immunocytochemistry/ Immunofluorescence: N-PAC Antibody [NBP2-38618]

Immunocytochemistry/Immunofluorescence: N-PAC Antibody [NBP2-38618] - Immunofluorescent staining of human cell line U-2 OS shows localization to nuclear speckles.
Immunohistochemistry-Paraffin: N-PAC Antibody [NBP2-38618]

Immunohistochemistry-Paraffin: N-PAC Antibody [NBP2-38618]

Immunohistochemistry-Paraffin: N-PAC Antibody [NBP2-38618] - Staining of human testis.
Immunohistochemistry: N-PAC Antibody [NBP2-38618]

Immunohistochemistry: N-PAC Antibody [NBP2-38618]

Immunohistochemistry: N-PAC Antibody [NBP2-38618] - Staining of human kidney shows strong nuclear and cytoplasmic positivity in cells in tubules and cells in glomeruli.
View 4 more images

Applications for N-PAC Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 ug/ml

Immunohistochemistry

1:50 - 1:200

Immunohistochemistry-Paraffin

1:50 - 1:200
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended. Immunocytochemistry/Immunofluorescence Fixation Permeabilization: Use PFA/Triton X-100.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: N-PAC

N-PAC may have oxidoreductase activity. Regulates p38 MAP kinase activity by mediating stress activation ofp38alpha/MAPK14 and specifically regulating MAPK14 signaling. Indirectly promotes phosphorylation of MAPK14 andactivation of ATF2. The phosphorylation of

Alternate Names

BM045, Cytokine-like nuclear factor N-PAC, Glyoxylate reductase 1 homolog, glyoxylate reductase 1 homolog (Arabidopsis), HIBDLnuclear protein 60 kDa, NP603-hydroxyisobutyrate dehydrogenase-like protein, N-PAC, nuclear protein 60kDa, Nuclear protein NP60, Nuclear protein of 60 kDa, putative oxidoreductase GLYR1

Gene Symbol

GLYR1

UniProt

Q49A26 (Human)

Additional N-PAC Products

Product Documents for N-PAC Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for N-PAC Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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