NAPE-PLD Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-87881

Novus Biologicals, part of Bio-Techne
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NBP2-87881
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Key Product Details

Species Reactivity

Human

Applications

Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit

Concentration

0.5 mg/ml

View all NAPE-PLD Antibodies »

Product Specifications

Immunogen

The immunogen is a synthetic peptide directed towards the C-terminal region of human NAPE-PLD. Peptide sequence: AFEEIGKRFGPFDLAAIPIGAYEPRWFMKYQHVDPEEAVRIHTDVQTKKS The peptide sequence for this immunogen was taken from within the described region.

Clonality

Polyclonal

Host

Rabbit

Scientific Data Images for NAPE-PLD Antibody

Western Blot: NAPE-PLD Antibody [NBP2-87881]

Western Blot: NAPE-PLD Antibody [NBP2-87881]

Western Blot: NAPE-PLD Antibody [NBP2-87881] - Host: Rabbit. Target Name: NAPEPLD. Sample Type: HCT116 Whole Cell lysates. Antibody Dilution: 1.0ug/ml

Applications for NAPE-PLD Antibody

Application
Recommended Usage

Western Blot

1.0 ug/ml

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS, 2% Sucrose

Preservative

0.09% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: NAPE-PLD

NAPE-PLD (also known as N-Acylphosphatidylethanolamine (NAPE)-hydrolyzing phospholipase D) is a membrane-bound phospholipase D type enzyme that catalyzes the release of N-acylethanolamine (NAE) from N-acyl-phosphatidylethanolamine (NAPE) in the second step of the biosynthesis of N-acylethanolamine. NAPE-PLD has been shown to be expressed by specific populations of neurons in the brain and targeted to axonal processes. Recent studies have suggested that NAEs generated by NAPE-PLD in axons may act as anterograde synaptic signaling molecules that regulate the activity of postsynaptic neurons. NAPE-PLD has also been shown to catalyze the hydrolysis of NAPE to generate OEA (oleoylethanolamide), a natural lipid amide that inhibits food intake in free-feeding rodents by prolonging latency to feed and postmeal interval.

Long Name

N-acyl-phosphatidylethanolamine-hydrolyzing phospholipase D

Alternate Names

C7orf18, EC 3.1.4.54, NAPEPLD

Gene Symbol

NAPEPLD

Additional NAPE-PLD Products

Product Documents for NAPE-PLD Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for NAPE-PLD Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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