NAPRT1 Antibody (CL0665)

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-52954

Novus Biologicals, part of Bio-Techne
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NBP2-52954
NBP2-52954-25ul
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Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Mouse (97%), Rat (96%). Backed by our 100% Guarantee.

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 Clone # CL0665

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all NAPRT1 Antibodies »

Product Summary for NAPRT1 Antibody (CL0665)

Immunogen

This antibody was developed against a recombinant protein corresponding to amino acids: PAFFEHLRALDCSEVTVRALPEGSLAFPGVPLLQVSGPLLVVQLLETPLLCLVSYASLVATNAARLRLIAGP

Epitope

PAFFEHLRALDCSEV

Reactivity Notes

Please note that this antibody is reactive to Mouse and derived from the same host, Mouse. Mouse-On-Mouse blocking reagent may be needed for IHC and ICC experiments to reduce high background signal. You can find these reagents under catalog numbers PK-2200-NB and MP-2400-NB. Please contact Technical Support if you have any questions

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Scientific Data Images for NAPRT1 Antibody (CL0665)

Western Blot: NAPRT1 Antibody (CL0665) [NBP2-52954]

Western Blot: NAPRT1 Antibody (CL0665) [NBP2-52954]

Western Blot: NAPRT1 Antibody (CL0665) [NBP2-52954] - Lane 1: Marker [kDa], Lane 2: Human liver tissue lysate
Immunohistochemistry-Paraffin: NAPRT1 Antibody (CL0665) [NBP2-52954]

Immunohistochemistry-Paraffin: NAPRT1 Antibody (CL0665) [NBP2-52954]

Immunohistochemistry-Paraffin: NAPRT1 Antibody (CL0665) [NBP2-52954] - Staining of human testis shows moderate cytoplasmic positivity in seminiferous tubules.
Immunohistochemistry-Paraffin: NAPRT1 Antibody (CL0665) [NBP2-52954]

Immunohistochemistry-Paraffin: NAPRT1 Antibody (CL0665) [NBP2-52954]

Immunohistochemistry-Paraffin: NAPRT1 Antibody (CL0665) [NBP2-52954] - Staining of human breast cancer shows positivity in tumor cells.
View 5 more images

Applications for NAPRT1 Antibody (CL0665)

Application
Recommended Usage

Immunohistochemistry

1:200 - 1:500

Immunohistochemistry-Paraffin

1:200 - 1:500

Western Blot

1 ug/ml
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: NAPRT1

Nicotinic acid (NA; niacin) is converted by nicotinic acid phosphoribosyltransferase (NAPRT; EC 2.4.2.11) to NA mononucleotide (NaMN), which is then converted to NA adenine dinucleotide (NaAD), and finally to nicotinamide adenine dinucleotide (NAD), which serves as a coenzyme in cellular redox reactions and is an essential component of a variety of processes in cellular metabolism including response to stress (Hara et al., 2007).[supplied by OMIM]

Alternate Names

EC 2.4.2.11, FHA-HIT-interacting protein, FHIP, NAPRTase, nicotinate phosphoribosyltransferase, nicotinate phosphoribosyltransferase domain containing 1, Nicotinate phosphoribosyltransferase domain-containing protein 1, nicotinic acid phosphoribosyltransferase, PP3856

Gene Symbol

NAPRT

Additional NAPRT1 Products

Product Documents for NAPRT1 Antibody (CL0665)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for NAPRT1 Antibody (CL0665)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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