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Napsin A Antibody (CL12954)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-18551

Novus Biologicals, part of Bio-Techne
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NBP3-18551-100ul
NBP3-18551-25ul

Key Product Details

Species Reactivity

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 Clone # CL12954

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Product Specifications

Immunogen

This antibody was developed against a sythetic peptide for O96009. Actual immunogen sequence is proprietary.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Scientific Data Images for Napsin A Antibody (CL12954)

Immunohistochemistry-Paraffin: Napsin A Antibody (CL12954) [NBP3-18551]

Immunohistochemistry-Paraffin: Napsin A Antibody (CL12954) [NBP3-18551]

Immunohistochemistry-Paraffin: Napsin A Antibody (CL12954) [NBP3-18551] - Staining of human cerebral cortex shows no positivity in neurons as expected.
Immunohistochemistry-Paraffin: Napsin A Antibody (CL12954) [NBP3-18551]

Immunohistochemistry-Paraffin: Napsin A Antibody (CL12954) [NBP3-18551]

Immunohistochemistry-Paraffin: Napsin A Antibody (CL12954) [NBP3-18551] - Analysis in human kidney and skeletal muscle tissues using NBP3-18551 antibody. Corresponding NAPSA RNA-seq data are presented for the same tissues.
Immunohistochemistry-Paraffin: Napsin A Antibody (CL12954) [NBP3-18551]

Immunohistochemistry-Paraffin: Napsin A Antibody (CL12954) [NBP3-18551]

Immunohistochemistry-Paraffin: Napsin A Antibody (CL12954) [NBP3-18551] - Staining of human ovarian cancer (clear cell carcinoma) shows moderate to strong granular cytoplasmic positivity in tumor cells.

Applications for Napsin A Antibody (CL12954)

Application
Recommended Usage

Immunohistochemistry

1:5000 - 1:10000

Immunohistochemistry-Paraffin

1:5000 - 1:10000
Application Notes
For use with IHC-Paraffin, HIER pH 6 retrieval is recommended.

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

PBS, pH 7.2, 40% glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Napsin A

Napsin is a pepsin-like aspartic proteinase, in the A1 clan of the AA clade of proteinases. Other AA family proteinases include Pepsin, cathepsin-D, cathepsin-E and rennin. Of these proteinases, napsin is most closely related to cathepsin-D, sharing 46% identity at the amino acid level. There are two closely related Napsins, napsin A and napsin B, with 85% overall identity at the amino acid level. There are three isoforms. Napsin-A is also termed napsin-1, or TA02, a Tumor Adenocarcinoma marker. Napsin A may be involved in processing of pneumocyte surfactant precursors.

Alternate Names

ASP4, KAP, NAPA, NAPSA, Napsin-1, SNAPA, TA01/TA02

Gene Symbol

NAPSA

Additional Napsin A Products

Product Documents for Napsin A Antibody (CL12954)

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for Napsin A Antibody (CL12954)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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